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Cell Death & Disease|April 28, 2018
Smad proteins differentially regulate obesity-induced glucose and lipid abnormalities and inflammation via class-specific control of AMPK-related kinase MPK38/MELK activityHyun-A Seong, Ravi Manoharan, Hyunjung Ha
The Journal of Biological Chemistry|October 25, 2008
Murine protein serine/threonine kinase 38 activates apoptosis signal-regulating kinase 1 via Thr 838 phosphorylationHaiyoung Jung, Hyun-A Seong, Hyunjung Ha
Scientific Reports|February 15, 2017
Zinc finger protein ZPR9 functions as an activator of AMPK-related serine/threonine kinase MPK38/MELK involved in ASK1/TGF-β/p53 signaling pathwaysHyun-A Seong, Ravi Manoharan, Hyunjung Ha
The Journal of Biological Chemistry|February 23, 2007
NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signalingHyun-A Seong, Haiyoung Jung, Hyunjung Ha
Oxidative Medicine and Cellular Longevity|June 1, 2018
Dual Roles of Serine-Threonine Kinase Receptor-Associated Protein (STRAP) in Redox-Sensitive Signaling Pathways Related to Cancer DevelopmentRavi Manoharan, Hyun-A Seong, Hyunjung Ha
Cell Cycle (Georgetown, Tex.)|December 9, 2014
A crucial role for the phosphorylation of STRAP at Ser(188) by MPK38 in STRAP-dependent cell death through ASK1, TGF-β, p53, and PI3K/PDK1 signaling pathwaysHyun-A Seong, Ravi Manoharan, Hyunjung Ha
Antioxidants & Redox Signaling|October 1, 2015
Coordinate Activation of Redox-Dependent ASK1/TGF-β Signaling by a Multiprotein Complex (MPK38, ASK1, SMADs, ZPR9, and TRX) Improves Glucose and Lipid Metabolism in MiceHyun-A Seong, Ravi Manoharan, Hyunjung Ha
The Journal of Biological Chemistry|March 21, 2003
Enhancement of B-MYB transcriptional activity by ZPR9, a novel zinc finger proteinHyun-A Seong, Kyong-Tai Kim, Hyunjung Ha
The Journal of Biological Chemistry|November 3, 2009
Serine-threonine kinase receptor-associated protein inhibits apoptosis signal-regulating kinase 1 function through direct interactionHaiyoung Jung, Hyun-A Seong, Ravi Manoharan, et al.
The Journal of Biological Chemistry|May 1, 2012
PDK1 protein phosphorylation at Thr354 by murine protein serine-threonine kinase 38 contributes to negative regulation of PDK1 protein activityHyun-A Seong, Haiyoung Jung, Ravi Manoharan, et al.
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