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Molecular Pharmacology|December 22, 2004
Modulation of UDP-glucuronosyltransferase function by cytochrome P450: evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4Shuso Takeda, Yuji Ishii, Megumi Iwanaga, et al.
British Journal of Clinical Pharmacology|March 18, 2006
Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidationVerawan Uchaipichat, Leanne K Winner, Peter I Mackenzie, et al.
Molecular Pharmacology|July 1, 2018
Intergenic Splicing between Four Adjacent <i>UGT</i> Genes (<i>2B15, 2B29P2, 2B17, 2B29P1</i>) Gives Rise to Variant UGT Proteins That Inhibit Glucuronidation via Protein-Protein InteractionsDong Gui Hu, Julie-Ann Hulin, Dhilushi D Wijayakumara, et al.
Biochemical Pharmacology|January 16, 2007
Amino terminal domains of human UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 associated with substrate selectivity and autoactivationBenjamin C Lewis, Peter I Mackenzie, David J Elliot, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 28, 2006
In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interactionAndrew Rowland, David J Elliot, J Andrew Williams, et al.
Biochemical and Biophysical Research Communications|February 26, 2020
Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGTYuu Miyauchi, Ayumi Kurita, Ryohei Yamashita, et al.
Cancer Research|January 15, 1997
Preclinical prediction of factors influencing the elimination of 5,6-dimethylxanthenone-4-acetic acid, a new anticancer drugJ O Miners, L Valente, K J Lillywhite, et al.
Chemical Research in Toxicology|September 21, 2007
Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: role of acyl glucuronide metabolites and glycation pathwaysHamish T Southwood, Yvette C DeGraaf, Peter I Mackenzie, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 2, 2024
Activation of Cryptic Donor Splice Sites within the UDP-Glucuronosyltransferase (UGT)1A First-Exon Region Generates Variant Transcripts That Encode UGT1A Proteins with Truncated Aglycone-Binding DomainsDong Gui Hu, Shashikanth Marri, Julie-Ann Hulin, et al.
Biochemical and Biophysical Research Communications|March 29, 1991
Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9M E Veronese, P I Mackenzie, C J Doecke, et al.
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