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Scientific Reports|May 27, 2024
Cardiac myosin inhibitor, CK-586, minimally reduces systolic function and ameliorates obstruction in feline hypertrophic cardiomyopathyVictor N Rivas, Amanda E Crofton, Carina E Jauregui, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 6, 2016
Highly selective inhibition of myosin motors provides the basis of potential therapeutic applicationSerena Sirigu, James J Hartman, Vicente José Planelles-Herrero, et al.
Circulation. Heart Failure|March 3, 2022
Developments in Exercise Capacity Assessment in Heart Failure Clinical Trials and the Rationale for the Design of METEORIC-HFGregory D Lewis, Kieran F Docherty, Adriaan A Voors, et al.
JACC. Cardiovascular Interventions|October 23, 2020
Baseline Functional Capacity and Transcatheter Mitral Valve Repair in Heart Failure With Secondary Mitral RegurgitationUmar I Malik, Andrew P Ambrosy, Ivy A Ku, et al.
Brain : a Journal of Neurology|May 30, 2013
Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathyCoen A C Ottenheijm, Danielle Buck, Josine M de Winter, et al.
European Heart Journal|August 31, 2025
Serum magnesium and outcomes in heart failure with reduced ejection fraction: the GALACTIC-HF trialMisato Chimura, Kieran F Docherty, Pardeep S Jhund, et al.
Journal of the American College of Cardiology|March 26, 2016
Acute Treatment With Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure: The ATOMIC-AHF StudyJohn R Teerlink, G Michael Felker, John J V McMurray, et al.
American Heart Journal|January 31, 2021
Rationale and design of the pragmatic randomized trial of icosapent ethyl for high cardiovascular risk adults (MITIGATE)Andrew P Ambrosy, Umar I Malik, Rachel C Thomas, et al.
JACC. Heart Failure|January 13, 2026
Lactate Dehydrogenase and Outcomes in Patients With HF and Reduced Ejection Fraction: Insights From GALACTIC-HFRyohei Ono, Misato Chimura, Kieran F Docherty, et al.
Journal of Medicinal Chemistry|October 4, 2021
Discovery of Aficamten (CK-274), a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic CardiomyopathyChihyuan Chuang, Scott Collibee, Luke Ashcraft, et al.
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