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ACS Medicinal Chemistry Letters
|
January 19, 2019
Aminopyrazole Carboxamide Bruton's Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning
Mark E Schnute, Stephen E Benoit, Ingrid P Buchler, et al.
Journal of Medicinal Chemistry
|
August 17, 2018
Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)
Andrew Fensome, Catherine M Ambler, Eric Arnold, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS)
Chris P Carron, John I Trujillo, Kirk L Olson, et al.
Nature Communications
|
March 10, 2026
Discovery of an ITK and TRK kinase inhibitor for the potential topical treatment of atopic dermatitis
Jennifer L Duffen, Kimberly K Crouse, Lin Ji, et al.
Journal of Medicinal Chemistry
|
September 22, 2025
Discovery of PF-07054894, a Potent Squaramide-Based CCR6 Antagonist Displaying High CXCR2 Selectivity
Mark E Schnute, Huixian Wu, John I Trujillo, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2025
Peptidylarginine Deiminase (PAD) Inhibitor Optimization through Displacement of a Trapped Water Molecule
Mark E Schnute, Gary M Chinigo, Kentaro Futatsugi, et al.
Journal of Medicinal Chemistry
|
August 22, 2018
Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist
Mark E Schnute, Mattias Wennerstål, Jennifer Alley, et al.
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Showing results (51-60 of 57) with videos related to
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Page
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This site can display upto 57 results.
ACS Medicinal Chemistry Letters
|
January 19, 2019
Aminopyrazole Carboxamide Bruton's Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning
Mark E Schnute, Stephen E Benoit, Ingrid P Buchler, et al.
Journal of Medicinal Chemistry
|
August 17, 2018
Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)
Andrew Fensome, Catherine M Ambler, Eric Arnold, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS)
Chris P Carron, John I Trujillo, Kirk L Olson, et al.
Nature Communications
|
March 10, 2026
Discovery of an ITK and TRK kinase inhibitor for the potential topical treatment of atopic dermatitis
Jennifer L Duffen, Kimberly K Crouse, Lin Ji, et al.
Journal of Medicinal Chemistry
|
September 22, 2025
Discovery of PF-07054894, a Potent Squaramide-Based CCR6 Antagonist Displaying High CXCR2 Selectivity
Mark E Schnute, Huixian Wu, John I Trujillo, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2025
Peptidylarginine Deiminase (PAD) Inhibitor Optimization through Displacement of a Trapped Water Molecule
Mark E Schnute, Gary M Chinigo, Kentaro Futatsugi, et al.
Journal of Medicinal Chemistry
|
August 22, 2018
Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist
Mark E Schnute, Mattias Wennerstål, Jennifer Alley, et al.
Page
of 6