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CPT: Pharmacometrics & Systems Pharmacology
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June 10, 2026
Physiologically Based Pharmacokinetic Model to Predict Drug-Drug Interactions With the Antibody-Drug Conjugate Trastuzumab Deruxtecan
Akiko Watanabe, Katherine L Gill, Kuan-Fu Chen, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
September 7, 2020
A Laboratory-Specific Scaling Factor to Predict the In Vivo Human Clearance of Aldehyde Oxidase Substrates
Mailys De Sousa Mendes, Alexandra L Orton, Helen E Humphries, et al.
International Journal of Molecular Sciences
|
September 13, 2025
Testing Strategies for Metabolite-Mediated Neurotoxicity
Julian Suess, Moritz Reinmoeller, Viktoria Magel, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
October 8, 2021
Development of physiologically-based pharmacokinetic models for standard of care and newer tuberculosis drugs
Helen Humphries, Lisa Almond, Alexander Berg, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
February 4, 2010
Excretion and metabolism of lersivirine (5-{[3,5-diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a next-generation non-nucleoside reverse transcriptase inhibitor, after administration of [14C]Lersivirine to healthy volunteers
Manoli Vourvahis, Michelle Gleave, Angus N R Nedderman, et al.
The AAPS Journal
|
March 20, 2019
Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations
Krishna K Machavaram, Chihiro Endo-Tsukude, Kimio Terao, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
December 26, 2024
Response to "Acetaminophen should be a critical reference hepatotoxin for evaluating human-relevant in vitro models"
Lucia A Livoti, Rowena Sison-Young, Dennis Reddyhoff, et al.
The AAPS Journal
|
November 4, 2025
Investigating Sulfotransferase Mediated Drug Interactions of Ethinylestradiol using a Physiologically Based Pharmacokinetic Model
Harry P Moore, Kuan-Fu Chen, Aki T Heikkinen, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
April 21, 2022
Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator
Peter J Kilford, Kuan-Fu Chen, Kim Crewe, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
November 7, 2024
Limitations of acetaminophen as a reference hepatotoxin for the evaluation of in vitro liver models
Lucia A Livoti, Rowena Sison-Young, Dennis Reddyhoff, et al.
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of 11
Search research articles
Search
Showing results (51-60 of 106) with videos related to
Sort By:
Page
of 11
CPT: Pharmacometrics & Systems Pharmacology
|
June 10, 2026
Physiologically Based Pharmacokinetic Model to Predict Drug-Drug Interactions With the Antibody-Drug Conjugate Trastuzumab Deruxtecan
Akiko Watanabe, Katherine L Gill, Kuan-Fu Chen, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
September 7, 2020
A Laboratory-Specific Scaling Factor to Predict the In Vivo Human Clearance of Aldehyde Oxidase Substrates
Mailys De Sousa Mendes, Alexandra L Orton, Helen E Humphries, et al.
International Journal of Molecular Sciences
|
September 13, 2025
Testing Strategies for Metabolite-Mediated Neurotoxicity
Julian Suess, Moritz Reinmoeller, Viktoria Magel, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
October 8, 2021
Development of physiologically-based pharmacokinetic models for standard of care and newer tuberculosis drugs
Helen Humphries, Lisa Almond, Alexander Berg, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
February 4, 2010
Excretion and metabolism of lersivirine (5-{[3,5-diethyl-1-(2-hydroxyethyl)(3,5-14C2)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile), a next-generation non-nucleoside reverse transcriptase inhibitor, after administration of [14C]Lersivirine to healthy volunteers
Manoli Vourvahis, Michelle Gleave, Angus N R Nedderman, et al.
The AAPS Journal
|
March 20, 2019
Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations
Krishna K Machavaram, Chihiro Endo-Tsukude, Kimio Terao, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
December 26, 2024
Response to "Acetaminophen should be a critical reference hepatotoxin for evaluating human-relevant in vitro models"
Lucia A Livoti, Rowena Sison-Young, Dennis Reddyhoff, et al.
The AAPS Journal
|
November 4, 2025
Investigating Sulfotransferase Mediated Drug Interactions of Ethinylestradiol using a Physiologically Based Pharmacokinetic Model
Harry P Moore, Kuan-Fu Chen, Aki T Heikkinen, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
April 21, 2022
Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator
Peter J Kilford, Kuan-Fu Chen, Kim Crewe, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
November 7, 2024
Limitations of acetaminophen as a reference hepatotoxin for the evaluation of in vitro liver models
Lucia A Livoti, Rowena Sison-Young, Dennis Reddyhoff, et al.
Page
of 11