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Journal of Molecular Biology|September 29, 2009
Crystal structures of Leishmania mexicana phosphoglycerate mutase suggest a one-metal mechanism and a new enzyme subclassMatthew W Nowicki, Buabarn Kuaprasert, Iain W McNae, et al.Journal of Medicinal Chemistry|March 23, 2011
Pyrazolo[4,3-d]pyrimidine bioisostere of roscovitine: evaluation of a novel selective inhibitor of cyclin-dependent kinases with antiproliferative activityRadek Jorda, Libor Havlícek, Iain W McNae, et al.The Biochemical Journal|May 12, 2018
An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensorMeng Yuan, Iain W McNae, Yiyuan Chen, et al.The Biochemical Journal|December 17, 2013
Pyruvate kinases have an intrinsic and conserved decarboxylase activityWenhe Zhong, Hugh P Morgan, Matthew W Nowicki, et al.Bioorganic & Medicinal Chemistry|April 5, 2008
Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysisMatthew W Nowicki, Lindsay B Tulloch, Liam Worralll, et al.Metallomics : Integrated Biometal Science|October 14, 2011
Phosphoglycerate mutase from Trypanosoma brucei is hyperactivated by cobalt in vitro, but not in vivoFazia Adyani Ahmad Fuad, Linda A Fothergill-Gilmore, Matthew W Nowicki, et al.The Biochemical Journal|September 27, 2018
Redox regulation of pyruvate kinase M2 by cysteine oxidation and S-nitrosationAlice Rose Mitchell, Meng Yuan, Hugh P Morgan, et al.Plos Biology|November 25, 2025
The novel GlcNAc 6-phosphate dehydratase NagS governs a metabolic checkpoint that controls nutrient signaling in StreptomycesChao Li, Mia Urem, Ioli Kotsogianni, et al.The Biochemical Journal|August 22, 2012
A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinaseHugh P Morgan, Martin J Walsh, Elizabeth A Blackburn, et al.Nature Communications|February 17, 2021
Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in miceIain W McNae, James Kinkead, Divya Malik, et al.Pageof 3