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Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics|June 25, 2014
Heterogeneity of leucine-rich repeat kinase 2 mutations: genetics, mechanisms and therapeutic implicationsIakov N Rudenko, Mark R Cookson
The Biochemical Journal|August 28, 2010
14-3-3 proteins are promising LRRK2 interactorsIakov N Rudenko, Mark R Cookson
BMC Medicine|February 25, 2012
Is inhibition of kinase activity the only therapeutic strategy for LRRK2-associated Parkinson's disease?Iakov N Rudenko, Ruth Chia, Mark R Cookson
Human Molecular Genetics|August 22, 2013
Hexokinase activity is required for recruitment of parkin to depolarized mitochondriaMelissa K McCoy, Alice Kaganovich, Iakov N Rudenko, et al.
The Biochemical Journal|May 23, 2012
The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutationIakov N Rudenko, Alice Kaganovich, David N Hauser, et al.
The Biochemical Journal|March 22, 2017
The G2385R risk factor for Parkinson's disease enhances CHIP-dependent intracellular degradation of LRRK2Iakov N Rudenko, Alice Kaganovich, Rebekah G Langston, et al.
Nature Communications|December 16, 2014
Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7Ruth Chia, Sara Haddock, Alexandra Beilina, et al.
Nature Neuroscience|February 19, 2013
mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortexAllissa A Dillman, David N Hauser, J Raphael Gibbs, et al.
The Biochemical Journal|August 14, 2013
Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycleEvy Lobbestael, Jing Zhao, Iakov N Rudenko, et al.
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