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Current Opinion in Pharmacology|June 10, 2015
MEK inhibitors beyond monotherapy: current and future developmentIan E Templeton, Luna MusibThe AAPS Journal|February 15, 2018
Pediatric Dose Selection and Utility of PBPK in Determining DoseIan E Templeton, Nicholas S Jones, Luna MusibClinical Pharmacology and Therapeutics|November 20, 2021
Time to Rethink the Current Paradigm for Assessing Kidney Function in Drug Development and BeyondAshish Sharma, Vaishali Sahasrabudhe, Luna Musib, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 21, 2011
Predictive utility of in vitro rifampin induction data generated in fresh and cryopreserved human hepatocytes, Fa2N-4, and HepaRG cellsIan E Templeton, J Brian Houston, Aleksandra GaletinJournal of Clinical Pharmacology|June 23, 2015
Effects of enzastaurin and its metabolites on the QT interval in cancer patientsPamela A Welch, Wee Teck Ng, Christelle L Darstein, et al.Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology|March 4, 2008
Enzastaurin, an oral serine/threonine kinase inhibitor, as second- or third-line therapy of non-small-cell lung cancerYun Oh, Roy S Herbst, Howard Burris, et al.The AAPS Journal|June 21, 2023
Evaluation of the Potential for Drug-Drug Interactions with Inhaled Itraconazole Using Physiologically Based Pharmacokinetic Modelling, Based on Phase 1 Clinical DataMackenzie Bergagnini-Kolev, Katie Kane, Ian E Templeton, et al.Molecular Pharmaceutics|September 10, 2013
Absolute bioavailability and effect of formulation change, food, or elevated pH with rabeprazole on cobimetinib absorption in healthy subjectsLuna Musib, Edna Choo, Yuzhong Deng, et al.Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|December 3, 2014
Determination of cobimetinib in human plasma using protein precipitation extraction and high-performance liquid chromatography coupled to mass spectrometryYuzhong Deng, Luna Musib, Edna Choo, et al.Clinical Pharmacokinetics|May 27, 2016
Evaluation of Cytochrome P450 3A4-Mediated Drug-Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and SimulationNageshwar R Budha, Tao Ji, Luna Musib, et al.Pageof 5