Showing results (1-10 of 266) with videos related to
Sort By:
Pageof 27
Current Topics in Medicinal Chemistry|March 16, 2011
Finding new hits in neglected disease projects: target or phenotypic based screening?Ian H Gilbert, Didier Leroy, Julie A FrearsonTrends in Parasitology|October 27, 2007
Target assessment for antiparasitic drug discoveryJulie A Frearson, Paul G Wyatt, Ian H Gilbert, et al.Malaria Journal|November 9, 2017
Screening a protein kinase inhibitor library against Plasmodium falciparumIrene Hallyburton, Raffaella Grimaldi, Andrew Woodland, et al.Bioorganic & Medicinal Chemistry|November 4, 2010
Acetazolamide-based fungal chitinase inhibitorsAlexander W Schüttelkopf, Ludovic Gros, David E Blair, et al.Chemmedchem|June 27, 2009
Synthesis and evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) analogues as inhibitors of trypanothione reductaseStephen Patterson, Deuan C Jones, Emma J Shanks, et al.Drug Discovery Today|October 2, 2009
HTS and hit finding in academia--from chemical genomics to drug discoveryJulie A Frearson, Iain T CollieChemmedchem|December 14, 2011
Design, synthesis and biological evaluation of Trypanosoma brucei trypanothione synthetase inhibitorsDaniel Spinks, Leah S Torrie, Stephen Thompson, et al.Journal of Medicinal Chemistry|August 20, 2011
Dihydroquinazolines as a novel class of Trypanosoma brucei trypanothione reductase inhibitors: discovery, synthesis, and characterization of their binding mode by protein crystallographyStephen Patterson, Magnus S Alphey, Deuan C Jones, et al.Chemmedchem|November 20, 2009
Investigation of trypanothione reductase as a drug target in Trypanosoma bruceiDaniel Spinks, Emma J Shanks, Laura A T Cleghorn, et al.The Journal of Biological Chemistry|October 16, 2009
Chemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasisLeah S Torrie, Susan Wyllie, Daniel Spinks, et al.Pageof 27