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Future Medicinal Chemistry|April 30, 2015
Small-molecule MDM2-p53 inhibitors: recent advancesBian Zhang, Bernard T Golding, Ian R Hardcastle
Annual Review of Pharmacology and Toxicology|January 25, 2002
Designing inhibitors of cyclin-dependent kinasesIan R Hardcastle, Bernard T Golding, Roger J Griffin
Future Medicinal Chemistry|May 31, 2018
Recent advances in CDK inhibitors for cancer therapyAmy B Heptinstall, Iws Adiyasa, Céline Cano, et al.
Organic & Biomolecular Chemistry|December 14, 2006
A new strategy for the synthesis of taurine derivatives using the 'safety-catch' principle for the protection of sulfonic acidsSonja Seeberger, Roger J Griffin, Ian R Hardcastle, et al.
Molecular Cancer Therapeutics|September 20, 2005
An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell linesMike I Walton, Stuart C Wilson, Ian R Hardcastle, et al.
Organic & Biomolecular Chemistry|May 8, 2010
Atropisomeric 8-arylchromen-4-ones exhibit enantioselective inhibition of the DNA-dependent protein kinase (DNA-PK)Céline Cano, Bernard T Golding, Karen Haggerty, et al.
Organic Letters|December 15, 2006
Judicious application of allyl protecting groups for the synthesis of 2-morpholin-4-yl-4-oxo-4H-chromen-8-yl triflate, a key precursor of DNA-dependent protein kinase inhibitorsSonsoles Rodriguez Aristegui, Marine Desage El-Murr, Bernard T Golding, et al.
Organic & Biomolecular Chemistry|May 8, 2010
Synthesis of sulfonamide-based kinase inhibitors from sulfonates by exploiting the abrogated SN2 reactivity of 2,2,2-trifluoroethoxysulfonatesChristopher Wong, Roger J Griffin, Ian R Hardcastle, et al.
Organic & Biomolecular Chemistry|February 6, 2013
Trifluoroethanol solvent facilitates selective N-7 methylation of purinesHonorine Lebraud, Celine Cano, Benoit Carbain, et al.
Chemical Biology & Drug Design|January 20, 2011
Understanding small-molecule binding to MDM2: insights into structural effects of isoindolinone inhibitors from NMR spectroscopyChristiane Riedinger, Martin E Noble, David J Wright, et al.
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