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Ian R Outhwaite

Showing results (1-10 of 10) with videos related to

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Elife|October 18, 2023
Probing conformational dynamics to understand kinase inhibitionIan R Outhwaite, Markus A Seeliger
Elife|November 30, 2020
Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformationXiaowei Hou, Ian R Outhwaite, Leanne Pedi, et al.
Biochemical Society Transactions|February 16, 2023
Allosteric regulation and inhibition of protein kinasesVictoria R Mingione, YiTing Paung, Ian R Outhwaite, et al.
Elife|December 4, 2023
Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargetingIan R Outhwaite, Sukrit Singh, Benedict-Tilman Berger, et al.
Biorxiv : the Preprint Server for Biology|January 30, 2023
Death by a Thousand Cuts â€" Combining Kinase Inhibitors for Selective Target Inhibition and Rational PolypharmacologyIan R Outhwaite, Sukrit Singh, Benedict-Tilman Berger, et al.
Journal of Molecular Biology|April 11, 2025
Resistance to Allosteric InhibitorsIan R Outhwaite, Isabelle Kwan, Ariel Leyte-Vidal, et al.
Medical Science Educator|September 26, 2022
Motivation to Impact: Medical Student Volunteerism in the COVID 19 PandemicHannah E Phillips, Rebecca B Jennings, Ian R Outhwaite, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 31, 2024
Lucanthone, a Potential PPT1 Inhibitor, Perturbs Stemness, Reduces Tumor Microtube Formation, and Slows the Growth of Temozolomide-Resistant Gliomas In VivoDaniel P Radin, Sophie Shifman, Ian R Outhwaite, et al.
Nature Chemical Biology|September 27, 2022
Discovery and molecular basis of subtype-selective cyclophilin inhibitorsAlexander A Peterson, Aziz M Rangwala, Manish K Thakur, et al.
Leukemia|July 31, 2024
Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminibAriel Leyte-Vidal, RosaAnna DeFilippis, Ian R Outhwaite, et al.
Pageof 1

Showing results (1-10 of 10) with videos related to

Sort By:
Pageof 1
Elife|October 18, 2023
Probing conformational dynamics to understand kinase inhibitionIan R Outhwaite, Markus A Seeliger
Elife|November 30, 2020
Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformationXiaowei Hou, Ian R Outhwaite, Leanne Pedi, et al.
Biochemical Society Transactions|February 16, 2023
Allosteric regulation and inhibition of protein kinasesVictoria R Mingione, YiTing Paung, Ian R Outhwaite, et al.
Elife|December 4, 2023
Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargetingIan R Outhwaite, Sukrit Singh, Benedict-Tilman Berger, et al.
Biorxiv : the Preprint Server for Biology|January 30, 2023
Death by a Thousand Cuts â€" Combining Kinase Inhibitors for Selective Target Inhibition and Rational PolypharmacologyIan R Outhwaite, Sukrit Singh, Benedict-Tilman Berger, et al.
Journal of Molecular Biology|April 11, 2025
Resistance to Allosteric InhibitorsIan R Outhwaite, Isabelle Kwan, Ariel Leyte-Vidal, et al.
Medical Science Educator|September 26, 2022
Motivation to Impact: Medical Student Volunteerism in the COVID 19 PandemicHannah E Phillips, Rebecca B Jennings, Ian R Outhwaite, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 31, 2024
Lucanthone, a Potential PPT1 Inhibitor, Perturbs Stemness, Reduces Tumor Microtube Formation, and Slows the Growth of Temozolomide-Resistant Gliomas In VivoDaniel P Radin, Sophie Shifman, Ian R Outhwaite, et al.
Nature Chemical Biology|September 27, 2022
Discovery and molecular basis of subtype-selective cyclophilin inhibitorsAlexander A Peterson, Aziz M Rangwala, Manish K Thakur, et al.
Leukemia|July 31, 2024
Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminibAriel Leyte-Vidal, RosaAnna DeFilippis, Ian R Outhwaite, et al.
Pageof 1