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Trends in Pharmacological Sciences|November 1, 2023
Ligand selectivity hotspots in serotonin GPCRsIcaro A Simon, Walden E Bjørn-Yoshimoto, Kasper Harpsøe, et al.Journal of Chemical Information and Modeling|October 13, 2023
PSW-Designer: An Open-Source Computational Platform for the Design and Virtual Screening of Photopharmacological LigandsIcaro A Simon, Evert J Homan, Maikel Wijtmans, et al.ACS Chemical Neuroscience|January 21, 2025
Synthesis, Pharmacological Characterization, and Binding Mode Analysis of 8-Hydroxy-Tetrahydroisoquinolines as 5-HT<sub>7</sub> Receptor Inverse AgonistsCamilla B Chan, Eline Pottie, Icaro A Simon, et al.ACS Chemical Neuroscience|July 20, 2023
Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT<sub>2A</sub> Receptor AgonistsEline Pottie, Christian B M Poulie, Icaro A Simon, et al.Journal of Medicinal Chemistry|September 13, 2022
Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT<sub>2A</sub> Receptor AgonistsChristian B M Poulie, Eline Pottie, Icaro A Simon, et al.Journal of the American Chemical Society|June 26, 2025
A Radiolabeled Photoswitchable G Protein-Coupled Receptor Antagonist Enlightens Ligand Binding Kinetics Associated with PhotoswitchingLars C P Binkhorst, Ivana Josimovic, Bas De Boer, et al.Molecular Cell|June 17, 2022
GPCRs steer G<sub>i</sub> and G<sub>s</sub> selectivity via TM5-TM6 switches as revealed by structures of serotonin receptorsSijie Huang, Peiyu Xu, Dan-Dan Shen, et al.Nature|March 25, 2021
Structural insights into the lipid and ligand regulation of serotonin receptorsPeiyu Xu, Sijie Huang, Huibing Zhang, et al.Molecular Pharmacology|February 12, 2024
Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3Aurelien M Zarca, Ilze Adlere, Cristina P Viciano, et al.Pageof 1