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Journal of Medicinal Chemistry
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April 5, 2017
Sustainable Practices in Medicinal Chemistry Part 2: Green by Design
Ignacio Aliagas, Raphaëlle Berger, Kristin Goldberg, et al.
Journal of Computer-Aided Molecular Design
|
April 30, 2015
An integrated suite of modeling tools that empower scientists in structure- and property-based drug design
Jianwen A Feng, Ignacio Aliagas, Philippe Bergeron, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 28, 2016
Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors
Wendy Lee, James J Crawford, Ignacio Aliagas, et al.
ACS Medicinal Chemistry Letters
|
June 24, 2015
Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series
Joachim Rudolph, Ignacio Aliagas, James J Crawford, et al.
Journal of Medicinal Chemistry
|
June 2, 2015
Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors
James J Crawford, Wendy Lee, Ignacio Aliagas, et al.
Journal of Medicinal Chemistry
|
May 1, 2009
A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B
Ignacio Aliagas-Martin, Dan Burdick, Laura Corson, et al.
Nature
|
February 5, 2010
RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
Georgia Hatzivassiliou, Kyung Song, Ivana Yen, et al.
ACS Medicinal Chemistry Letters
|
December 30, 2015
Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety
Chudi O Ndubaku, James J Crawford, Joy Drobnick, et al.
Journal of Medicinal Chemistry
|
February 17, 2012
Potent and selective aminopyrimidine-based B-Raf inhibitors with favorable physicochemical and pharmacokinetic properties
Simon Mathieu, Stefan N Gradl, Li Ren, et al.
Journal of Medicinal Chemistry
|
May 12, 2016
Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window
Joachim Rudolph, Lesley J Murray, Chudi O Ndubaku, et al.
Page
of 3
Search research articles
Search
Showing results (11-20 of 24) with videos related to
Sort By:
Page
of 3
Journal of Medicinal Chemistry
|
April 5, 2017
Sustainable Practices in Medicinal Chemistry Part 2: Green by Design
Ignacio Aliagas, Raphaëlle Berger, Kristin Goldberg, et al.
Journal of Computer-Aided Molecular Design
|
April 30, 2015
An integrated suite of modeling tools that empower scientists in structure- and property-based drug design
Jianwen A Feng, Ignacio Aliagas, Philippe Bergeron, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 28, 2016
Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors
Wendy Lee, James J Crawford, Ignacio Aliagas, et al.
ACS Medicinal Chemistry Letters
|
June 24, 2015
Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series
Joachim Rudolph, Ignacio Aliagas, James J Crawford, et al.
Journal of Medicinal Chemistry
|
June 2, 2015
Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors
James J Crawford, Wendy Lee, Ignacio Aliagas, et al.
Journal of Medicinal Chemistry
|
May 1, 2009
A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B
Ignacio Aliagas-Martin, Dan Burdick, Laura Corson, et al.
Nature
|
February 5, 2010
RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
Georgia Hatzivassiliou, Kyung Song, Ivana Yen, et al.
ACS Medicinal Chemistry Letters
|
December 30, 2015
Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety
Chudi O Ndubaku, James J Crawford, Joy Drobnick, et al.
Journal of Medicinal Chemistry
|
February 17, 2012
Potent and selective aminopyrimidine-based B-Raf inhibitors with favorable physicochemical and pharmacokinetic properties
Simon Mathieu, Stefan N Gradl, Li Ren, et al.
Journal of Medicinal Chemistry
|
May 12, 2016
Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window
Joachim Rudolph, Lesley J Murray, Chudi O Ndubaku, et al.
Page
of 3