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Plos Biology|November 27, 2019
Loss of adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22Yu Chen, Maud Vandereyken, Ian P Newton, et al.The Journal of Biological Chemistry|August 8, 2019
A strategy for the selection of monovalent antibodies that span protein dimer interfacesJamie B Spangler, Ignacio Moraga, Kevin M Jude, et al.Cell Reports|December 28, 2020
CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene LociJonathan Martinez-Fabregas, Luopin Wang, Elizabeth Pohler, et al.Elife|May 13, 2017
Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimersIgnacio Moraga, Jamie B Spangler, Juan L Mendoza, et al.Science Advances|December 14, 2016
Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signalingChangjiang You, Tatiana T Marquez-Lago, Christian Paolo Richter, et al.Nature Communications|March 7, 2024
Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiencyScott Gardner, Yibo Jin, Paul K Fyfe, et al.Science Signaling|November 12, 2015
Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potencyIgnacio Moraga, David Richter, Stephan Wilmes, et al.Journal of Immunology (Baltimore, Md. : 1950)|April 20, 2010
CpG inhibits pro-B cell expansion through a cathepsin B-dependent mechanismAna Inés Lalanne, Ignacio Moraga, Yi Hao, et al.Science Signaling|September 16, 2020
Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand dosesClaire Gorby, Junel Sotolongo Bellón, Stephan Wilmes, et al.Elife|November 28, 2019
Kinetics of cytokine receptor trafficking determine signaling and functional selectivityJonathan Martinez-Fabregas, Stephan Wilmes, Luopin Wang, et al.Pageof 4