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Nature Immunology|October 30, 2012
Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15Aaron M Ring, Jian-Xin Lin, Dan Feng, et al.Cell|August 23, 2011
Structural linkage between ligand discrimination and receptor activation by type I interferonsChristoph Thomas, Ignacio Moraga, Doron Levin, et al.Nature Communications|July 15, 2017
Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartmentsDavid Richter, Ignacio Moraga, Hauke Winkelmann, et al.Immunity|March 23, 2017
The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional PlasticityJuan L Mendoza, William M Schneider, Hans-Heinrich Hoffmann, et al.Proceedings of the National Academy of Sciences of the United States of America|August 8, 2022
Engineered IL13 variants direct specificity of IL13Rα2-targeted CAR T cell therapyLawrence A Stern, Sharareh Gholamin, Ignacio Moraga, et al.Nature|March 27, 2012
Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'Aron M Levin, Darren L Bates, Aaron M Ring, et al.Elife|April 19, 2021
Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responsesStephan Wilmes, Polly-Anne Jeffrey, Jonathan Martinez-Fabregas, et al.Proceedings of the National Academy of Sciences of the United States of America|January 1, 2021
Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitorsLu Cui, Ignacio Moraga, Tristan Lerbs, et al.Nature Chemical Biology|October 30, 2012
Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkinesIlkka S Junttila, Remi J Creusot, Ignacio Moraga, et al.Science (New York, N.Y.)|February 8, 2020
Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutationsStephan Wilmes, Maximillian Hafer, Joni Vuorio, et al.Pageof 4