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Organic & Biomolecular Chemistry|January 5, 2008
Designer aminoglycosides: the race to develop improved antibiotics and compounds for the treatment of human genetic diseasesMariana Hainrichson, Igor Nudelman, Timor Baasov
Methods in Enzymology|September 7, 2010
Aminoglycosides redesign strategies for improved antibiotics and compounds for treatment of human genetic diseasesVarvara Pokrovskaya, Igor Nudelman, Jeyakumar Kandasamy, et al.
Bioorganic & Medicinal Chemistry|April 23, 2010
Repairing faulty genes by aminoglycosides: development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutationsIgor Nudelman, Dana Glikin, Boris Smolkin, et al.
Human Genetics|July 27, 2007
In vitro and ex vivo suppression by aminoglycosides of PCDH15 nonsense mutations underlying type 1 Usher syndromeAnnie Rebibo-Sabbah, Igor Nudelman, Zubair M Ahmed, et al.
Antimicrobial Agents and Chemotherapy|November 8, 2006
Overexpression and initial characterization of the chromosomal aminoglycoside 3'-O-phosphotransferase APH(3')-IIb from Pseudomonas aeruginosaMariana Hainrichson, Orit Yaniv, Marina Cherniavsky, et al.
Journal of Molecular Medicine (Berlin, Germany)|December 2, 2010
Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse modelCornelia Brendel, Valery Belakhov, Hauke Werner, et al.
Bioorganic & Medicinal Chemistry Letters|September 26, 2006
Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutationsIgor Nudelman, Annie Rebibo-Sabbah, Dalia Shallom-Shezifi, et al.
Chembiochem : a European Journal of Chemical Biology|August 21, 2007
Differential selectivity of natural and synthetic aminoglycosides towards the eukaryotic and prokaryotic decoding A sitesJiro Kondo, Mariana Hainrichson, Igor Nudelman, et al.
Plos One|June 23, 2011
Ex vivo treatment with a novel synthetic aminoglycoside NB54 in primary fibroblasts from Rett syndrome patients suppresses MECP2 nonsense mutationsManuela Vecsler, Bruria Ben Zeev, Igor Nudelman, et al.
Investigative Ophthalmology & Visual Science|July 31, 2010
Beneficial read-through of a USH1C nonsense mutation by designed aminoglycoside NB30 in the retinaTobias Goldmann, Annie Rebibo-Sabbah, Nora Overlack, et al.
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