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The Journal of Biological Chemistry|February 5, 2025
Phosphodiesterase 5 expression in photoreceptors rescues retinal degeneration induced by deregulation of membrane guanylyl cyclaseAlexander M Dizhoor, Shinya Sato, Zhuokai Luo, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|September 13, 2013
cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel functionJianhua Xu, Lynsie Morris, Arjun Thapa, et al.
The Journal of Biological Chemistry|January 10, 2019
A G86R mutation in the calcium-sensor protein GCAP1 alters regulation of retinal guanylyl cyclase and causes dominant cone-rod degenerationIgor V Peshenko, Artur V Cideciyan, Alexander Sumaroka, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|August 19, 2007
Constitutive excitation by Gly90Asp rhodopsin rescues rods from degeneration caused by elevated production of cGMP in the darkMichael L Woodruff, Elena V Olshevskaya, Andrey B Savchenko, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|July 9, 2004
The Y99C mutation in guanylyl cyclase-activating protein 1 increases intracellular Ca2+ and causes photoreceptor degeneration in transgenic miceElena V Olshevskaya, Peter D Calvert, Michael L Woodruff, et al.
Investigative Ophthalmology & Visual Science|June 6, 2025
Clinical and Biochemical Characterization of Specific GUCY2D Alleles Associated With a Rare Form of Night BlindnessRola Ba-Abbad, Igor V Peshenko, Malena Daich Varela, et al.
Iscience|November 14, 2024
Erratum: Safety and improved efficacy signals following gene therapy in childhood blindness caused by GUCY2D mutationsSamuel G Jacobson, Artur V Cideciyan, Allen C Ho, et al.
Human Gene Therapy|August 7, 2015
Gene Therapy Fully Restores Vision to the All-Cone Nrl(-/-) Gucy2e(-/-) Mouse Model of Leber Congenital Amaurosis-1Sanford L Boye, James J Peterson, Shreyasi Choudhury, et al.
Human Molecular Genetics|October 5, 2012
Determining consequences of retinal membrane guanylyl cyclase (RetGC1) deficiency in human Leber congenital amaurosis en route to therapy: residual cone-photoreceptor vision correlates with biochemical properties of the mutantsSamuel G Jacobson, Artur V Cideciyan, Igor V Peshenko, et al.
Investigative Ophthalmology & Visual Science|April 28, 2006
Effects of low AIPL1 expression on phototransduction in rodsClint L Makino, Xiao-Hong Wen, Norman Michaud, et al.
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