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Plos One|June 10, 2010
Structural and dynamical effects induced by the anticancer drug topotecan on the human topoisomerase I - DNA complexGiordano Mancini, Ilda D'Annessa, Andrea Coletta, et al.Nucleic Acids Research|September 6, 2008
A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistanceCarmen Losasso, Erica Cretaio, Paola Fiorani, et al.Nucleic Acids Research|September 4, 2008
Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulationsGiovanni Chillemi, Ilda D'Annessa, Paola Fiorani, et al.Organic & Biomolecular Chemistry|May 4, 2018
Chemo-enzymatic synthesis of (E)-2,3-diaryl-5-styryl-trans-2,3-dihydrobenzofuran-based scaffolds and their in vitro and in silico evaluation as a novel sub-family of potential allosteric modulators of the 90 kDa heat shock protein (Hsp90)Ivan Bassanini, Ilda D'Annessa, Massimo Costa, et al.Journal of Molecular Modeling|October 13, 2011
Mapping multiple potential ATP binding sites on the matrix side of the bovine ADP/ATP carrier by the combined use of MD simulation and dockingDaniele Di Marino, Francesco Oteri, Blasco Morozzo della Rocca, et al.Biochimica Et Biophysica Acta|October 8, 2013
The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlationIlda D'Annessa, Cinzia Tesauro, Zhenxing Wang, et al.Biochimica Et Biophysica Acta|April 26, 2015
Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientationZhenxing Wang, Ilda D'Annessa, Cinzia Tesauro, et al.Nucleic Acids Research|July 25, 2014
Simulations of DNA topoisomerase 1B bound to supercoiled DNA reveal changes in the flexibility pattern of the enzyme and a secondary protein-DNA binding siteIlda D'Annessa, Andrea Coletta, Thana Sutthibutpong, et al.Archives of Biochemistry and Biophysics|December 25, 2012
A derivative of the natural compound kakuol affects DNA relaxation of topoisomerase IB inhibiting the cleavage reactionSilvia Castelli, Sara Vieira, Ilda D'Annessa, et al.Plos One|December 14, 2012
Binding of an Indenoisoquinoline to the topoisomerase-DNA complex induces reduction of linker mobility and strengthening of protein-DNA interactionGiordano Mancini, Ilda D'Annessa, Andrea Coletta, et al.Pageof 5