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Bioorganic & Medicinal Chemistry|December 25, 2016
Construction of a 3D-shaped, natural product like fragment library by fragmentation and diversification of natural productsHorst Prescher, Guido Koch, Tim Schuhmann, et al.Chemmedchem|May 8, 2016
Design and Development of a Cyclic Decapeptide Scaffold with Suitable Properties for Bioavailability and Oral ExposureMarianne Fouché, Michael Schäfer, Jörg Berghausen, et al.Acta Crystallographica. Section F, Structural Biology and Crystallization Communications|March 9, 2010
Crystallization and X-ray diffraction studies of cellobiose phosphorylase from Cellulomonas udaAnnelies Van Hoorebeke, Jan Stout, John Kyndt, et al.European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V|May 8, 2018
Bioinspired co-crystals of Imatinib providing enhanced kinetic solubilityMaude Reggane, Johannes Wiest, Marco Saedtler, et al.Journal of Medicinal Chemistry|April 6, 2021
Use of Intramolecular 1,5-Sulfur-Oxygen and 1,5-Sulfur-Halogen Interactions in the Design of N-Methyl-5-aryl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 Splicing ModulatorsJake Axford, Moo Je Sung, John Manchester, et al.Journal of Medicinal Chemistry|January 24, 2018
Discovery of the First Potent, Selective, and Orally Bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) Inhibitor Displaying Pronounced Immunomodulatory Effects In VivoJuraj Velcicky, Ursula Bodendorf, Pascal Rigollier, et al.Bioorganic & Medicinal Chemistry Letters|February 21, 2017
Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hitCyrille S Kounde, Hui-Quan Yeo, Qing-Yin Wang, et al.ACS Medicinal Chemistry Letters|April 17, 2015
Lead optimization of spiropyrazolopyridones: a new and potent class of dengue virus inhibitorsBin Zou, Wai Ling Chan, Mei Ding, et al.Journal of Medicinal Chemistry|November 30, 2020
Discovery of Potent, Highly Selective, and In Vivo Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold MorphingCarole Pissot Soldermann, Oliver Simic, Martin Renatus, et al.ACS Medicinal Chemistry Letters|February 16, 2017
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1Julian R Levell, Thomas Caferro, Gregg Chenail, et al.Pageof 4