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Cells|June 26, 2024
Down-Regulation of AKT Proteins Slows the Growth of Mutant-KRAS Pancreatic TumorsChuankai Chen, Ya-Ping Jiang, Inchul You, et al.
Biorxiv : the Preprint Server for Biology|May 15, 2024
Down-regulation of AKT proteins slows the growth of mutant-KRAS pancreatic tumorsChuankai Chen, Ya-Ping Jiang, Inchul You, et al.
Cell Chemical Biology|December 21, 2019
Discovery of an AKT Degrader with Prolonged Inhibition of Downstream SignalingInchul You, Emily C Erickson, Katherine A Donovan, et al.
ACS Chemical Biology|August 25, 2022
Redirecting the Neo-Substrate Specificity of Cereblon-Targeting PROTACs to HeliosAlyssa L Verano, Inchul You, Katherine A Donovan, et al.
Cell Chemical Biology|August 11, 2023
Targeted kinase degradation via the KLHDC2 ubiquitin E3 ligaseYounghoon Kim, Pooreum Seo, Eunhye Jeon, et al.
Cell Chemical Biology|October 11, 2022
Acute pharmacological degradation of ERK5 does not inhibit cellular immune response or proliferationInchul You, Katherine A Donovan, Noah M Krupnick, et al.
Nature Chemical Biology|April 6, 2026
Charged molecular glue discovery enabled by targeted degron displayZhe Zhuang, Woong Sub Byun, Jakub Chrustowicz, et al.
Journal of the American Chemical Society|November 5, 2024
Discovery of CRBN-Dependent WEE1 Molecular Glue Degraders from a Multicomponent Combinatorial LibraryHlib Razumkov, Zixuan Jiang, Kheewoong Baek, et al.
Biorxiv : the Preprint Server for Biology|May 15, 2024
Discovery of CRBN-dependent WEE1 Molecular Glue Degraders from a Multicomponent Combinatorial LibraryHlib Razumkov, Zixuan Jiang, Kheewoong Baek, et al.
Science Signaling|February 27, 2024
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradationEmily C Erickson, Inchul You, Grace Perry, et al.
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