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Cancers|October 23, 2021
The Chemokine-Based Peptide, CXCL9(74-103), Inhibits Angiogenesis by Blocking Heparan Sulfate Proteoglycan-Mediated Signaling of Multiple Endothelial Growth FactorsAlexandra De Zutter, Helena Crijns, Nele Berghmans, et al.Journal of Medicinal Chemistry|October 29, 2025
Selective and Orally Bioavailable Dipeptidyl Peptidase 9 Inhibitors with Potent Pyroptosis Induction PropertiesNicolò Filippi, Kathleen Mertens, Joni De Loose, et al.Frontiers in Chemistry|January 23, 2023
Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteasesAlba Ramos-Llorca, Lisse Decraecker, Valérie M Y Cacheux, et al.Journal of Medicinal Chemistry|March 28, 2024
5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived FunctionsHenri T Pätsi, Tommi P Kilpeläinen, Mikael Jumppanen, et al.Journal of Clinical Medicine|March 25, 2022
Activation of the Carboxypeptidase U (CPU, TAFIa, CPB2) System in Patients with SARS-CoV-2 Infection Could Contribute to COVID-19 Hypofibrinolytic State and Disease Severity PrognosisKaren Claesen, Yani Sim, An Bracke, et al.Clinica Chimica Acta; International Journal of Clinical Chemistry|March 14, 2022
Proline-specific peptidase activities (DPP4, PRCP, FAP and PREP) in plasma of hospitalized COVID-19 patientsAn Bracke, Emilie De Hert, Michelle De Bruyn, et al.Arteriosclerosis, Thrombosis, and Vascular Biology|January 3, 2020
Native, Intact Glucagon-Like Peptide 1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow ConditionsMarieke Sternkopf, Magdolna Nagy, Constance C F M J Baaten, et al.European Journal of Medicinal Chemistry|December 27, 2025
In vitro kinetic profiling by enzymatic approaches to select FAPIs with a long residence timeEmile Verhulst, Pawel Brzeminski, Anke de Groot, et al.The Journal of Clinical Investigation|July 23, 2024
Intercellular interaction between FAP+ fibroblasts and CD150+ inflammatory monocytes mediates fibrostenosis in Crohn's diseaseBo-Jun Ke, Saeed Abdurahiman, Francesca Biscu, et al.Pageof 13