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Frontiers in Neuroscience|June 3, 2016
Multi-Target Directed Donepezil-Like Ligands for Alzheimer's DiseaseMercedes Unzeta, Gerard Esteban, Irene Bolea, et al.Journal of Medicinal Chemistry|October 26, 2011
Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's diseaseIrene Bolea, Jordi Juárez-Jiménez, Cristóbal de Los Ríos, et al.European Journal of Medicinal Chemistry|February 18, 2014
Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's diseaseOscar M Bautista-Aguilera, Gerard Esteban, Irene Bolea, et al.European Journal of Medicinal Chemistry|June 15, 2011
Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer's diseaseAbdelouahid Samadi, Mourad Chioua, Irene Bolea, et al.European Journal of Medicinal Chemistry|April 17, 2012
Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amineAbdelouahid Samadi, Cristóbal de los Ríos, Irene Bolea, et al.Food & Function|March 11, 2015
Catecholaminergic and cholinergic systems of mouse brain are modulated by LMN diet, rich in theobromine, polyphenols and polyunsaturated fatty acidsLaura Fernández-Fernández, Gerard Esteban, Mercedes Giralt, et al.Elife|August 13, 2019
Defined neuronal populations drive fatal phenotype in a mouse model of Leigh syndromeIrene Bolea, Alejandro Gella, Elisenda Sanz, et al.Behavioural Brain Research|November 29, 2011
LMN diet, rich in polyphenols and polyunsaturated fatty acids, improves mouse cognitive decline associated with aging and Alzheimer's diseaseLaura Fernández-Fernández, Gemma Comes, Irene Bolea, et al.Frontiers in Neuroscience|December 10, 2016
Monoaminergic and Histaminergic Strategies and Treatments in Brain DiseasesGiuseppe Di Giovanni, Dubravka Svob Strac, Montse Sole, et al.Drug Development Research|September 1, 2019
Synthesis, biological evaluation, and molecular modeling of nitrile-containing compounds: Exploring multiple activities as anti-Alzheimer agentsDaniel Silva, Eduarda Mendes, Eleanor J Summers, et al.Pageof 2