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Antimicrobial Agents and Chemotherapy|July 31, 2013
Evaluation of the effect of cobicistat on the in vitro renal transport and cytotoxicity potential of tenofovirKirsten M Stray, Rujuta A Bam, Gabriel Birkus, et al.
Kidney International|March 21, 2014
Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistatEve-Irene Lepist, Xuexiang Zhang, Jia Hao, et al.
Journal of Clinical Pharmacology|December 31, 2013
Pharmacokinetics of cobicistat boosted-elvitegravir administered in combination with rosuvastatinJoseph M Custodio, Hui Wang, Jia Hao, et al.
Molecular Pharmaceutics|November 4, 2015
Metformin Is a Substrate and Inhibitor of the Human Thiamine Transporter, THTR-2 (SLC19A3)Xiaomin Liang, Huan-Chieh Chien, Sook Wah Yee, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 8, 2013
Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1Eve-Irene Lepist, Vijaya L Damaraju, Jing Zhang, et al.
Antimicrobial Agents and Chemotherapy|January 15, 2014
Metabolism and pharmacokinetics of the anti-hepatitis C virus nucleotide prodrug GS-6620Eisuke Murakami, Ting Wang, Darius Babusis, et al.
Journal of Medicinal Chemistry|July 18, 2018
Atropisomerism by Design: Discovery of a Selective and Stable Phosphoinositide 3-Kinase (PI3K) β InhibitorJayaraman Chandrasekhar, Ryan Dick, Joshua Van Veldhuizen, et al.
ACS Medicinal Chemistry Letters|June 20, 2020
Discovery of an Atropisomeric PI3Kβ Selective Inhibitor through Optimization of the Hinge Binding MotifStephane Perreault, Fatima Arjmand, Jayaraman Chandrasekhar, et al.
Journal of Medicinal Chemistry|January 21, 2017
Discovery of a Phosphoinositide 3-Kinase (PI3K) β/δ Inhibitor for the Treatment of Phosphatase and Tensin Homolog (PTEN) Deficient Tumors: Building PI3Kβ Potency in a PI3Kδ-Selective Template by Targeting Nonconserved Asp856Stephane Perreault, Jayaraman Chandrasekhar, Zhi-Hua Cui, et al.
Journal of Medicinal Chemistry|September 24, 2016
Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic StabilityLeena Patel, Jayaraman Chandrasekhar, Jerry Evarts, et al.
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