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Biochemical Pharmacology|May 25, 2015
Identification of potent and compartment-selective small molecule furin inhibitors using cell-based assaysBruno Ramos-Molina, Adam N Lick, Elias H Blanco, et al.Proceedings of the National Academy of Sciences of the United States of America|July 30, 2002
Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defectsXiaorong Zhu, An Zhou, Arunangsu Dey, et al.Molecular Pharmacology|June 22, 2013
Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning librariesClemencia Pinilla, Bruce S Edwards, Jon R Appel, et al.Chemmedchem|October 24, 2017
Optimization of Substrate-Analogue Furin InhibitorsTeodora Ivanova, Kornelia Hardes, Stephanie Kallis, et al.Archives of Biochemistry and Biophysics|May 30, 2009
A study of human furin specificity using synthetic peptides derived from natural substrates, and effects of potassium ionsMario A Izidoro, Iuri E Gouvea, Jorge A N Santos, et al.Plos One|October 2, 2014
A novel familial mutation in the PCSK1 gene that alters the oxyanion hole residue of proprotein convertase 1/3 and impairs its enzymatic activityMichael Wilschanski, Montaser Abbasi, Elias Blanco, et al.Journal of Medicinal Chemistry|April 22, 2021
Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput "Unbiased" Screening CampaignSkye R Doering, Katie Freeman, Ginamarie Debevec, et al.Chemmedchem|January 26, 2019
Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase FurinThuy Van Lam van, Teodora Ivanova, Kornelia Hardes, et al.Journal of Medicinal Chemistry|November 7, 2012
The Multi-Leu peptide inhibitor discriminates between PACE4 and furin and exhibits antiproliferative effects on prostate cancer cellsChristine Levesque, Martin Fugère, Anna Kwiatkowska, et al.Journal of Medicinal Chemistry|February 13, 2014
Identification of tetrapeptides from a mixture based positional scanning library that can restore nM full agonist function of the L106P, I69T, I102S, A219V, C271Y, and C271R human melanocortin-4 polymorphic receptors (hMC4Rs)Erica M Haslach, Huisuo Huang, Marvin Dirain, et al.Pageof 12