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International Journal of Molecular Sciences|June 4, 2020
Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease TherapyÓscar M Bautista-Aguilera, Lhassane Ismaili, Mourad Chioua, et al.
Scientific Reports|August 27, 2020
Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia modelsBeatriz Chamorro, Daniel Diez-Iriepa, Belén Merás-Sáiz, et al.
European Journal of Medicinal Chemistry|June 12, 2019
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatmentSerena Montanari, Ali Mokhtar Mahmoud, Letizia Pruccoli, et al.
ACS Pharmacology & Translational Science|November 21, 2022
The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer AgentsTim Keuler, Carina Lemke, Paul W Elsinghorst, et al.
European Journal of Medicinal Chemistry|June 30, 2018
Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's diseaseMourad Chioua, Eleonora Buzzi, Ignacio Moraleda, et al.
European Journal of Medicinal Chemistry|December 6, 2016
Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapyYoussef Dgachi, Olga Sokolov, Vincent Luzet, et al.
ACS Chemical Neuroscience|February 6, 2013
Synthesis, pharmacological assessment, and molecular modeling of acetylcholinesterase/butyrylcholinesterase inhibitors: effect against amyloid-β-induced neurotoxicityDaniel Silva, Mourad Chioua, Abdelouahid Samadi, et al.
European Journal of Medicinal Chemistry|July 17, 2012
Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's diseaseEmna Maalej, Fakher Chabchoub, María Jesús Oset-Gasque, et al.
European Journal of Medicinal Chemistry|May 13, 2014
Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's diseaseLi Wang, Gerard Esteban, Masaki Ojima, et al.
European Journal of Medicinal Chemistry|April 23, 2026
Structure-based virtual screening, in vitro and in silico analysis identified novel potent m6A demethylase FTO inhibitors as promising neurotherapeutic agentsAlba Irisarri, Aina Bellver-Sanchis, Bhanwar Singh Choudhary, et al.
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