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Molecular Informatics
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December 22, 2016
Quantitative Structure-activity Relationship (QSAR) Models for Docking Score Correction
Yoshifumi Fukunishi, Satoshi Yamasaki, Isao Yasumatsu, et al.
Journal of Chemical Information and Modeling
|
April 9, 2021
Flexibility and Cell Permeability of Cyclic Ras-Inhibitor Peptides Revealed by the Coupled Nosé-Hoover Equation
Kei Moritsugu, Koh Takeuchi, Narutoshi Kamiya, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 3, 2010
Discovery of imidazo[1,2-b]pyridazine derivatives as IKKbeta inhibitors. Part 1: Hit-to-lead study and structure-activity relationship
Hiroki Shimizu, Shinji Tanaka, Tadashi Toki, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 15, 2011
Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 2: improvement of potency in vitro and in vivo
Hiroki Shimizu, Isao Yasumatsu, Tomoaki Hamada, et al.
Bioorganic & Medicinal Chemistry
|
May 18, 2017
Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator
Yumi Matsui, Isao Yasumatsu, Takashi Asahi, et al.
ACS Medicinal Chemistry Letters
|
July 17, 2024
Optimization of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors, Leading to the Potent DS08701581
Toru Taniguchi, Isao Yasumatsu, Hiroaki Inagaki, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 12, 2020
Discovery of novel histone lysine methyltransferase G9a/GLP (EHMT2/1) inhibitors: Design, synthesis, and structure-activity relationships of 2,4-diamino-6-methylpyrimidines
Katsushi Katayama, Ken Ishii, Eisuke Tsuda, et al.
Acta Crystallographica. Section F, Structural Biology Communications
|
March 3, 2018
A novel inhibitor stabilizes the inactive conformation of MAPK-interacting kinase 1
Yumi Matsui, Isao Yasumatsu, Ken Ichi Yoshida, et al.
ACS Medicinal Chemistry Letters
|
January 25, 2021
Discovery of DS79932728: A Potent, Orally Available G9a/GLP Inhibitor for Treating β-Thalassemia and Sickle Cell Disease
Katsushi Katayama, Ken Ishii, Hideki Terashima, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 8, 2023
Synthesis, activity, and their relationships of 2,4-diaminonicotinamide derivatives as EGFR inhibitors targeting C797S mutation
Hideaki Kageji, Takayuki Momose, Yasuhito Nagamoto, et al.
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of 2
Search research articles
Search
Showing results (1-10 of 15) with videos related to
Sort By:
Page
of 2
Molecular Informatics
|
December 22, 2016
Quantitative Structure-activity Relationship (QSAR) Models for Docking Score Correction
Yoshifumi Fukunishi, Satoshi Yamasaki, Isao Yasumatsu, et al.
Journal of Chemical Information and Modeling
|
April 9, 2021
Flexibility and Cell Permeability of Cyclic Ras-Inhibitor Peptides Revealed by the Coupled Nosé-Hoover Equation
Kei Moritsugu, Koh Takeuchi, Narutoshi Kamiya, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 3, 2010
Discovery of imidazo[1,2-b]pyridazine derivatives as IKKbeta inhibitors. Part 1: Hit-to-lead study and structure-activity relationship
Hiroki Shimizu, Shinji Tanaka, Tadashi Toki, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 15, 2011
Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 2: improvement of potency in vitro and in vivo
Hiroki Shimizu, Isao Yasumatsu, Tomoaki Hamada, et al.
Bioorganic & Medicinal Chemistry
|
May 18, 2017
Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator
Yumi Matsui, Isao Yasumatsu, Takashi Asahi, et al.
ACS Medicinal Chemistry Letters
|
July 17, 2024
Optimization of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors, Leading to the Potent DS08701581
Toru Taniguchi, Isao Yasumatsu, Hiroaki Inagaki, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 12, 2020
Discovery of novel histone lysine methyltransferase G9a/GLP (EHMT2/1) inhibitors: Design, synthesis, and structure-activity relationships of 2,4-diamino-6-methylpyrimidines
Katsushi Katayama, Ken Ishii, Eisuke Tsuda, et al.
Acta Crystallographica. Section F, Structural Biology Communications
|
March 3, 2018
A novel inhibitor stabilizes the inactive conformation of MAPK-interacting kinase 1
Yumi Matsui, Isao Yasumatsu, Ken Ichi Yoshida, et al.
ACS Medicinal Chemistry Letters
|
January 25, 2021
Discovery of DS79932728: A Potent, Orally Available G9a/GLP Inhibitor for Treating β-Thalassemia and Sickle Cell Disease
Katsushi Katayama, Ken Ishii, Hideki Terashima, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 8, 2023
Synthesis, activity, and their relationships of 2,4-diaminonicotinamide derivatives as EGFR inhibitors targeting C797S mutation
Hideaki Kageji, Takayuki Momose, Yasuhito Nagamoto, et al.
Page
of 2