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Journal of Molecular Biology|March 8, 2025
Rethinking RNA Modifications: Therapeutic Strategies for Targeting Dysregulated RNAIsobel E Bowles, Esteban A Orellana
RNA (New York, N.Y.)|December 10, 2023
A tRNA-specific function for tRNA methyltransferase Trm10 is associated with a new tRNA quality control mechanism in Saccharomyces cerevisiaeIsobel E Bowles, Jane E Jackman
Accounts of Chemical Research|December 4, 2023
Diversity in Biological Function and Mechanism of the tRNA Methyltransferase Trm10Isobel E Bowles, Jane E Jackman
The Journal of Biological Chemistry|August 21, 2022
Tied up in knots: Untangling substrate recognition by the SPOUT methyltransferasesSarah E Strassler, Isobel E Bowles, Debayan Dey, et al.
Biorxiv : the Preprint Server for Biology|February 27, 2026
Targeting tRNA-Arg-TCT-4-1 suppresses cancer cell growth and tumorigenesisEsteban A Orellana, Isobel E Bowles, Xin Yang, et al.
Biorxiv : the Preprint Server for Biology|February 13, 2023
tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10Sarah E Strassler, Isobel E Bowles, Aiswarya Krishnamohan, et al.
The Journal of Biological Chemistry|November 10, 2023
tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10Sarah E Strassler, Isobel E Bowles, Aiswarya Krishnamohan, et al.
Protein Science : a Publication of the Protein Society|April 29, 2021
Transition metal cation inhibition of Mycobacterium tuberculosis esterase RV0045CIsobel E Bowles, Emily H Pool, Benjamin S Lancaster, et al.
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