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Molecular Cancer Therapeutics|May 6, 2010
Metformin in cancer therapy: a new perspective for an old antidiabetic drug?Issam Ben Sahra, Yannick Le Marchand-Brustel, Jean-François Tanti, et al.Current Opinion in Oncology|November 30, 2011
Metformin and cancer therapyFrédéric Bost, Issam Ben Sahra, Yannick Le Marchand-Brustel, et al.Science (New York, N.Y.)|February 23, 2013
Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1Issam Ben-Sahra, Jessica J Howell, John M Asara, et al.Biochemical Society Transactions|July 19, 2013
A growing role for mTOR in promoting anabolic metabolismJessica J Howell, Stéphane J H Ricoult, Issam Ben-Sahra, et al.Biorxiv : the Preprint Server for Biology|June 6, 2025
Rate Limiting Enzymes in Nucleotide Metabolism Synchronize Nucleotide Biosynthesis and Chromatin FormationShashank Srivastava, Daniela Samaniego-Castruita, Sakshi Khurana, et al.Science (New York, N.Y.)|February 26, 2016
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycleIssam Ben-Sahra, Gerta Hoxhaj, Stéphane J H Ricoult, et al.Biorxiv : the Preprint Server for Biology|April 3, 2026
MLL3/4 methyltransferases regulate the differentiation of pluripotent stem cells via cellular respirationSuza Mohammad Nur, Yunbo Jia, Muyi Ye, et al.Molecular Cell|December 4, 2025
Rate-limiting enzymes in nucleotide metabolism synchronize nucleotide biosynthesis and chromatin formationShashank Srivastava, Daniela Samaniego-Castruita, Shubhi Srivastava, et al.Nature Communications|November 28, 2013
The TSC-mTOR pathway regulates macrophage polarizationVanessa Byles, Anthony J Covarrubias, Issam Ben-Sahra, et al.Cell Reports|November 2, 2017
The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide LevelsGerta Hoxhaj, James Hughes-Hallett, Rebecca C Timson, et al.Pageof 8