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Molecular Metabolism|July 25, 2021
Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulinVanessa Byles, Yann Cormerais, Krystle Kalafut, et al.Molecular Cell|June 30, 2022
The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesisEunus S Ali, Anna Lipońska, Brendan P O'Hara, et al.JCI Insight|April 24, 2023
Longitudinal trajectories of branched chain amino acids through young adulthood and diabetes in later lifeKonrad T Sawicki, Hongyan Ning, Norrina B Allen, et al.Cancer Letters|April 25, 2013
The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cellsCélia Rosilio, Nadia Lounnas, Marielle Nebout, et al.The Journal of Clinical Investigation|March 22, 2022
ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in miceHidemichi Kouzu, Yuki Tatekoshi, Hsiang-Chun Chang, et al.Cell Metabolism|January 1, 2019
Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue RepairShuang Zhang, Samuel Weinberg, Matthew DeBerge, et al.Biorxiv : the Preprint Server for Biology|March 10, 2025
Parallel multiOMIC analysis reveals glutamine deprivation enhances directed differentiation of renal organoidsIman Sarami, Katherine E Hekman, Ashwani Kumar Gupta, et al.Science Advances|February 11, 2021
NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemiaShashank Srivastava, Umakant Sahu, Yalu Zhou, et al.Biorxiv : the Preprint Server for Biology|March 10, 2025
Succinate dehydrogenase activity supports de novo purine synthesisMushtaq A Nengroo, Austin T Klein, Heather S Carr, et al.Science (New York, N.Y.)|March 28, 2024
Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesisUmakant Sahu, Elodie Villa, Colleen R Reczek, et al.Pageof 8