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Molecular Cancer Therapeutics|August 24, 2023
Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath TumorKathryn M Lemberg, Eunus S Ali, Marcela Krecmerova, et al.Brain : a Journal of Neurology|April 15, 2021
De novo purine biosynthesis is a major driver of chemoresistance in glioblastomaJack M Shireman, Fatemeh Atashi, Gina Lee, et al.Elife|February 20, 2016
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activationAnthony J Covarrubias, Halil Ibrahim Aksoylar, Jiujiu Yu, et al.Cancer Research|May 9, 2019
PGC1α Inhibits Polyamine Synthesis to Suppress Prostate Cancer AggressivenessLisa Kaminski, Stéphanie Torrino, Maeva Dufies, et al.Oncotarget|October 15, 2017
Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cellsHilaire C Lam, Heng-Jia Liu, Christian V Baglini, et al.Cell|November 26, 2024
Mechano-dependent sorbitol accumulation supports biomolecular condensateStephanie Torrino, William M Oldham, Andrés R Tejedor, et al.Proceedings of the National Academy of Sciences of the United States of America|June 20, 2018
mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial functionTatsuya Sato, Hsiang-Chun Chang, Marina Bayeva, et al.Scientific Reports|July 13, 2017
The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cellsCamille Loubiere, Stephan Clavel, Jerome Gilleron, et al.Nature Medicine|February 14, 2017
The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemiaNina Fenouille, Christopher F Bassil, Issam Ben-Sahra, et al.Cancer Research|June 8, 2021
Dual Covalent Inhibition of PKM and IMPDH Targets Metabolism in Cutaneous Metastatic MelanomaMarwa Zerhouni, Anthony R Martin, Nathan Furstoss, et al.Pageof 8