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Cell Death & Disease|October 6, 2025
Adipocyte-specific Mlkl knockout mitigates obesity-induced metabolic dysfunction by enhancing mitochondrial functionsJuliette Tokgozoglu, Valeria Pistorio, Mirko Minini, et al.Nature Communications|November 9, 2021
Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic signal-induced dysfunctionBaptiste Lamarthée, Armance Marchal, Soëli Charbonnier, et al.Nature Communications|March 3, 2026
Pharmacological stabilization of hypoxia-inducible factor 1-α dampens the interferon response and promotes glycolysis in Aicardi-Goutières syndromeMaxime Batignes, Marine Luka, Surabhi Jagtap, et al.Nature Communications|June 17, 2021
Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signalingCelia de la Calle Arregui, Ana Belén Plata-Gómez, Nerea Deleyto-Seldas, et al.EMBO Molecular Medicine|March 30, 2026
The lipid transfer protein STARD7 controls intestinal tumor development in a context-dependent mannerKateryna Shostak, Yu Chen, Chloé Maurizy, et al.Science Immunology|November 14, 2025
An islet-resident macrophage antioxidant program preserves β cell physiologyAmélie Grosjean, Aude Jalon, Claire Leveau, et al.Developmental Cell|June 29, 2022
Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLDRomain Donne, Maëva Saroul-Ainama, Pierre Cordier, et al.The Journal of Experimental Medicine|September 15, 2023
Hemifacial myohyperplasia is due to somatic muscular PIK3CA gain-of-function mutations and responds to pharmacological inhibitionCharles Bayard, Eleonora Segna, Maxime Taverne, et al.Signal Transduction and Targeted Therapy|June 16, 2024
Targeted therapy for capillary-venous malformationsLola Zerbib, Sophia Ladraa, Antoine Fraissenon, et al.Science Advances|December 9, 2022
PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruptionSophia Ladraa, Lola Zerbib, Charles Bayard, et al.Pageof 10