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Assay and Drug Development Technologies
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May 21, 2010
A plate-based assay to measure cellular ERK substrate phosphorylation: utility for drug discovery of the MAPK-signaling cascade
Sreemathy Ramaswamy, Ivana Yen, Steve Sideris, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 3, 2014
Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1
Lewis Gazzard, Brent Appleton, Kerry Chapman, et al.
Cancer Cell
|
August 27, 2014
Structure of the BRAF-MEK complex reveals a kinase activity independent role for BRAF in MAPK signaling
Jacob R Haling, Jawahar Sudhamsu, Ivana Yen, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 8, 2015
4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase
Emily J Hanan, Matt Baumgardner, Marian C Bryan, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 4, 2014
Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase
Benjamin P Fauber, Peter S Dragovich, Jinhua Chen, et al.
Molecular Cancer Therapeutics
|
July 23, 2013
Combination drug scheduling defines a "window of opportunity" for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900
Elizabeth Blackwood, Jennifer Epler, Ivana Yen, et al.
Cell Chemical Biology
|
February 11, 2023
Ternary complex dissociation kinetics contribute to mutant-selective EGFR degradation
Scott C Rosenberg, Frances Shanahan, Sayumi Yamazoe, et al.
Cancer Cell
|
October 10, 2018
Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors
Ivana Yen, Frances Shanahan, Mark Merchant, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 10, 2013
Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase
Benjamin P Fauber, Peter S Dragovich, Jinhua Chen, et al.
Cancer Cell
|
March 22, 2016
Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2
Scott A Foster, Daniel M Whalen, Ayşegül Özen, et al.
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Search research articles
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Showing results (1-10 of 28) with videos related to
Sort By:
Page
of 3
Assay and Drug Development Technologies
|
May 21, 2010
A plate-based assay to measure cellular ERK substrate phosphorylation: utility for drug discovery of the MAPK-signaling cascade
Sreemathy Ramaswamy, Ivana Yen, Steve Sideris, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 3, 2014
Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1
Lewis Gazzard, Brent Appleton, Kerry Chapman, et al.
Cancer Cell
|
August 27, 2014
Structure of the BRAF-MEK complex reveals a kinase activity independent role for BRAF in MAPK signaling
Jacob R Haling, Jawahar Sudhamsu, Ivana Yen, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 8, 2015
4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase
Emily J Hanan, Matt Baumgardner, Marian C Bryan, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 4, 2014
Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase
Benjamin P Fauber, Peter S Dragovich, Jinhua Chen, et al.
Molecular Cancer Therapeutics
|
July 23, 2013
Combination drug scheduling defines a "window of opportunity" for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900
Elizabeth Blackwood, Jennifer Epler, Ivana Yen, et al.
Cell Chemical Biology
|
February 11, 2023
Ternary complex dissociation kinetics contribute to mutant-selective EGFR degradation
Scott C Rosenberg, Frances Shanahan, Sayumi Yamazoe, et al.
Cancer Cell
|
October 10, 2018
Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors
Ivana Yen, Frances Shanahan, Mark Merchant, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 10, 2013
Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase
Benjamin P Fauber, Peter S Dragovich, Jinhua Chen, et al.
Cancer Cell
|
March 22, 2016
Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2
Scott A Foster, Daniel M Whalen, Ayşegül Özen, et al.
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of 3