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ACS Chemical Neuroscience|November 14, 2014
The melatonin-N,N-dibenzyl(N-methyl)amine hybrid ITH91/IQM157 affords neuroprotection in an in vitro Alzheimer's model via hemo-oxygenase-1 inductionIzaskun Buendia, Javier Egea, Esther Parada, et al.
Biochemical Pharmacology|July 28, 2015
Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase I inductionElisa Navarro, Izaskun Buendia, Esther Parada, et al.
Antioxidants & Redox Signaling|January 15, 2013
The microglial α7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2Esther Parada, Javier Egea, Izaskun Buendia, et al.
British Journal of Pharmacology|November 27, 2014
Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of actionJavier Egea, Izaskun Buendia, Esther Parada, et al.
Redox Biology|July 21, 2018
Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathyAna I Rojo, Marta Pajares, Angel J García-Yagüe, et al.
Future Medicinal Chemistry|October 27, 2015
New melatonin-cinnamate hybrids as multi-target drugs for neurodegenerative diseases: Nrf2-induction, antioxidant effect and neuroprotectionIzaskun Buendia, Elisa Navarro, Patrycja Michalska, et al.
Aging Cell|September 30, 2015
CALHM1 and its polymorphism P86L differentially control Ca²⁺homeostasis, mitogen-activated protein kinase signaling, and cell vulnerability upon exposure to amyloid βAna José Moreno-Ortega, Izaskun Buendia, Lamia Mouhid, et al.
Neuropharmacology|July 19, 2015
Neuroprotective mechanism of the novel melatonin derivative Neu-P11 in brain ischemia related modelsIzaskun Buendia, Vanessa Gómez-Rangel, Laura González-Lafuente, et al.
Antioxidants (Basel, Switzerland)|July 26, 2020
Antioxidant, Anti-inflammatory and Neuroprotective Profiles of Novel 1,4-Dihydropyridine Derivatives for the Treatment of Alzheimer's DiseasePatrycja Michalska, Paloma Mayo, Cristina Fernández-Mendívil, et al.
Journal of Thrombosis and Haemostasis : JTH|June 1, 2021
Factor XII protects neurons from apoptosis by epidermal and hepatocyte growth factor receptor-dependent mechanismsEugénie Garnier, Damien Levard, Carine Ali, et al.
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