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J A Hartley

Showing results (81-90 of 116) with videos related to

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Anti-Cancer Drug Design|December 1, 1994
Structure-activity relationship of a series of nitrogen mustard- and pyrrole-containing minor groove-binding agents related to distamycinM D Wyatt, B J Garbiras, M K Haskell, et al.
Journal of Medicinal Chemistry|January 31, 1997
Cross-linking and sequence specific alkylation of DNA by aziridinyl quinones. 2. Structure requirements for sequence selectivityR H Hargreaves, S P Mayalarp, J Butler, et al.
Molecular Pharmacology|March 1, 1988
Characteristics of the interaction of anthrapyrazole anticancer agents with deoxyribonucleic acids: structural requirements for DNA binding, intercalation, and photosensitizationJ A Hartley, K Reszka, E T Zuo, et al.
Biochemistry|April 6, 1993
Two structurally related diaziridinylbenzoquinones preferentially cross-link DNA at different sites upon reduction with DT-diaphoraseM D Berardini, R L Souhami, C S Lee, et al.
Anti-Cancer Drug Design|February 25, 1998
Chemical, biochemical and pharmacological activity of the novel sterically hindered platinum co-ordination complex, cis-[amminedichloro(2-methylpyridine)] platinum(II) (AMD473)J Holford, F Raynaud, B A Murrer, et al.
Nucleic Acids Research|January 11, 1995
DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycinM Broggini, H M Coley, N Mongelli, et al.
Biochemical Pharmacology|February 7, 1997
KW-2149 (7-N-[2-[gamma-L-glutamylamino]ethyldithioethyl]mitomycin C). A new mitomycin C analogue activated by serumJ R Masters, R J Know, J A Hartley, et al.
Nucleic Acids Research|September 11, 1987
alpha-DNA-V. Parallel annealing, handedness and conformation of the duplex of the unnatural alpha-hexadeoxyribonucleotide alpha-[d(CpApTpGpCpG)] with its beta-complement beta-[d(GpTpApCpGpC)] deduced from high field 1H-NMRF Morvan, B Rayner, J L Imbach, et al.
Biochemistry|March 24, 1992
Alteration in DNA cross-linking and sequence selectivity of a series of aziridinylbenzoquinones after enzymatic reduction by DT-diaphoraseC S Lee, J A Hartley, M D Berardini, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|April 1, 1999
Measurement of DNA cross-linking in patients on ifosfamide therapy using the single cell gel electrophoresis (comet) assayJ M Hartley, V J Spanswick, M Gander, et al.
Pageof 12

Showing results (81-90 of 116) with videos related to

Sort By:
Pageof 12
Anti-Cancer Drug Design|December 1, 1994
Structure-activity relationship of a series of nitrogen mustard- and pyrrole-containing minor groove-binding agents related to distamycinM D Wyatt, B J Garbiras, M K Haskell, et al.
Journal of Medicinal Chemistry|January 31, 1997
Cross-linking and sequence specific alkylation of DNA by aziridinyl quinones. 2. Structure requirements for sequence selectivityR H Hargreaves, S P Mayalarp, J Butler, et al.
Molecular Pharmacology|March 1, 1988
Characteristics of the interaction of anthrapyrazole anticancer agents with deoxyribonucleic acids: structural requirements for DNA binding, intercalation, and photosensitizationJ A Hartley, K Reszka, E T Zuo, et al.
Biochemistry|April 6, 1993
Two structurally related diaziridinylbenzoquinones preferentially cross-link DNA at different sites upon reduction with DT-diaphoraseM D Berardini, R L Souhami, C S Lee, et al.
Anti-Cancer Drug Design|February 25, 1998
Chemical, biochemical and pharmacological activity of the novel sterically hindered platinum co-ordination complex, cis-[amminedichloro(2-methylpyridine)] platinum(II) (AMD473)J Holford, F Raynaud, B A Murrer, et al.
Nucleic Acids Research|January 11, 1995
DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycinM Broggini, H M Coley, N Mongelli, et al.
Biochemical Pharmacology|February 7, 1997
KW-2149 (7-N-[2-[gamma-L-glutamylamino]ethyldithioethyl]mitomycin C). A new mitomycin C analogue activated by serumJ R Masters, R J Know, J A Hartley, et al.
Nucleic Acids Research|September 11, 1987
alpha-DNA-V. Parallel annealing, handedness and conformation of the duplex of the unnatural alpha-hexadeoxyribonucleotide alpha-[d(CpApTpGpCpG)] with its beta-complement beta-[d(GpTpApCpGpC)] deduced from high field 1H-NMRF Morvan, B Rayner, J L Imbach, et al.
Biochemistry|March 24, 1992
Alteration in DNA cross-linking and sequence selectivity of a series of aziridinylbenzoquinones after enzymatic reduction by DT-diaphoraseC S Lee, J A Hartley, M D Berardini, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|April 1, 1999
Measurement of DNA cross-linking in patients on ifosfamide therapy using the single cell gel electrophoresis (comet) assayJ M Hartley, V J Spanswick, M Gander, et al.
Pageof 12