J A Miller|E C Miller - JoVE Visualize

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Carcinogenesis|July 1, 1988

The essential role of microsomal deacetylase activity in the metabolic activation, DNA-(deoxyguanosin-8-yl)-2-aminofluorene adduct formation and initiation of liver tumors by N-hydroxy-2-acetylaminofluorene in the livers of infant male B6C3F1 miceC C Lai, E C Miller, J A Miller, et al.

Carcinogenesis|February 1, 1991

7-Sulfooxymethyl-12-methylbenz[a]anthracene is an electrophilic mutagen, but does not appear to play a role in carcinogenesis by 7,12-dimethylbenz[a]anthracene or 7-hydroxymethyl-12-methylbenz[a]anthraceneY J Surh, A Liem, E C Miller, et al.

Cancer Research|July 1, 1981

N2 atom of guanine and N6 atom of adenine residues as sites for covalent binding of metabolically activated 1'-hydroxysafrole to mouse liver DNA in vivoD H Phillips, J A Miller, E C Miller, et al.

Carcinogenesis|March 1, 1987

Initiation of hepatocarcinogenesis in infant male B6C3F1 mice by N-hydroxy-2-aminofluorene or N-hydroxy-2-acetylaminofluorene depends primarily on metabolism to N-sulfooxy-2-aminofluorene and formation of DNA-(deoxyguanosin-8-yl)-2-aminofluorene adductsC C Lai, E C Miller, J A Miller, et al.

Carcinogenesis|April 1, 1987

Inhibition by pentachlorophenol of the initiating and promoting activities of 1'-hydroxysafrole for the formation of enzyme-altered foci and tumors in rat liverE W Boberg, A Liem, E C Miller, et al.

Cancer Research|January 1, 1979

Promotion by dietary phenobarbital of hepatocarcinogenesis by 2-methyl-N,N-dimethyl-4-aminoazobenzene in the ratT Kitagawa, H C Pitot, E C Miller, et al.

Biochemical and Biophysical Research Communications|October 15, 1990

The strong hepatocarcinogenicity of the electrophilic and mutagenic metabolite 6-sulfooxymethylbenzo[a]pyrene and its formation of benzylic DNA adducts in the livers of infant male B6C3F1 miceY J Surh, A Liem, E C Miller, et al.

Biochemical Pharmacology|January 15, 1991

Age- and sex-related differences in activation of the carcinogen 7-hydroxymethyl-12-methylbenz[a]anthracene to an electrophilic sulfuric acid ester metabolite in rats. Possible involvement of hydroxysteroid sulfotransferase activityY J Surh, A Liem, E C Miller, et al.

Carcinogenesis|November 1, 1986

Identification and quantitation of hepatic DNA adducts formed in B6C3F1 mice from 1'-hydroxy-2',3'-dehydroestragole: comparison of the adducts detected with the 1'-3H-labelled carcinogen and by 32P-postlabellingT R Fennell, U Juhl, E C Miller, et al.

Journal of the National Cancer Institute|February 1, 1982

Cholangiocellular carcinomas induced in Syrian golden hamsters administered aflatoxin B1 in large dosesM R Moore, H C Pitot, E C Miller, et al.

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Carcinogenesis|July 1, 1988

The essential role of microsomal deacetylase activity in the metabolic activation, DNA-(deoxyguanosin-8-yl)-2-aminofluorene adduct formation and initiation of liver tumors by N-hydroxy-2-acetylaminofluorene in the livers of infant male B6C3F1 miceC C Lai, E C Miller, J A Miller, et al.

Carcinogenesis|February 1, 1991

7-Sulfooxymethyl-12-methylbenz[a]anthracene is an electrophilic mutagen, but does not appear to play a role in carcinogenesis by 7,12-dimethylbenz[a]anthracene or 7-hydroxymethyl-12-methylbenz[a]anthraceneY J Surh, A Liem, E C Miller, et al.

Cancer Research|July 1, 1981

N2 atom of guanine and N6 atom of adenine residues as sites for covalent binding of metabolically activated 1'-hydroxysafrole to mouse liver DNA in vivoD H Phillips, J A Miller, E C Miller, et al.

Carcinogenesis|March 1, 1987

Initiation of hepatocarcinogenesis in infant male B6C3F1 mice by N-hydroxy-2-aminofluorene or N-hydroxy-2-acetylaminofluorene depends primarily on metabolism to N-sulfooxy-2-aminofluorene and formation of DNA-(deoxyguanosin-8-yl)-2-aminofluorene adductsC C Lai, E C Miller, J A Miller, et al.

Carcinogenesis|April 1, 1987

Inhibition by pentachlorophenol of the initiating and promoting activities of 1'-hydroxysafrole for the formation of enzyme-altered foci and tumors in rat liverE W Boberg, A Liem, E C Miller, et al.

Cancer Research|January 1, 1979

Promotion by dietary phenobarbital of hepatocarcinogenesis by 2-methyl-N,N-dimethyl-4-aminoazobenzene in the ratT Kitagawa, H C Pitot, E C Miller, et al.

Biochemical and Biophysical Research Communications|October 15, 1990

The strong hepatocarcinogenicity of the electrophilic and mutagenic metabolite 6-sulfooxymethylbenzo[a]pyrene and its formation of benzylic DNA adducts in the livers of infant male B6C3F1 miceY J Surh, A Liem, E C Miller, et al.

Biochemical Pharmacology|January 15, 1991

Age- and sex-related differences in activation of the carcinogen 7-hydroxymethyl-12-methylbenz[a]anthracene to an electrophilic sulfuric acid ester metabolite in rats. Possible involvement of hydroxysteroid sulfotransferase activityY J Surh, A Liem, E C Miller, et al.

Carcinogenesis|November 1, 1986

Identification and quantitation of hepatic DNA adducts formed in B6C3F1 mice from 1'-hydroxy-2',3'-dehydroestragole: comparison of the adducts detected with the 1'-3H-labelled carcinogen and by 32P-postlabellingT R Fennell, U Juhl, E C Miller, et al.

Journal of the National Cancer Institute|February 1, 1982

Cholangiocellular carcinomas induced in Syrian golden hamsters administered aflatoxin B1 in large dosesM R Moore, H C Pitot, E C Miller, et al.

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