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Biochemistry|April 22, 1997
Structure-based design of a general class of mechanism-based inhibitors of the serine proteinases employing a novel amino acid-derived heterocyclic scaffoldW C Groutas, R Kuang, R Venkataraman, et al.
Biochimica Et Biophysica Acta|November 29, 1994
Mechanism-based inhibition of human leukocyte elastase and cathepsin G by substituted dihydrouracilsW C Groutas, H Huang, J B Epp, et al.
Bioorganic & Medicinal Chemistry|July 29, 1998
Potent and specific inhibition of human leukocyte elastase, cathepsin G and proteinase 3 by sulfone derivatives employing the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffoldW C Groutas, R Kuang, S Ruan, et al.
Archives of Biochemistry and Biophysics|April 1, 1992
Inhibitors of human neutrophil cathepsin G: structural and biochemical studiesW C Groutas, M J Brubaker, R Venkataraman, et al.
Virology|August 31, 2000
Exploiting polymerase promiscuity: A simple colorimetric RNA polymerase assayW Vassiliou, J B Epp, B B Wang, et al.
Bioorganic & Medicinal Chemistry|September 1, 1996
Design, synthesis, and in vitro inhibitory activity toward human leukocyte elastase, cathepsin G, and proteinase 3 of saccharin-derived sulfones and congenersW C Groutas, J B Epp, R Venkataraman, et al.
Bioorganic & Medicinal Chemistry|February 1, 1995
The Gabriel-Colman rearrangement in biological systems: design, synthesis and biological evaluation of phthalimide and saccharin derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3W C Groutas, L S Chong, R Venkataraman, et al.
Journal of Medicinal Chemistry|October 15, 1993
Efficient inhibition of human leukocyte elastase and cathepsin G by saccharin derivativesW C Groutas, N Houser-Archield, L S Chong, et al.
Archives of Biochemistry and Biophysics|August 15, 1996
Amino acid-derived phthalimide and saccharin derivatives as inhibitors of human leukocyte elastase, cathepsin G, and proteinase 3W C Groutas, L S Chong, R Venkataraman, et al.
Bioorganic & Medicinal Chemistry|April 1, 1995
Design, synthesis and biological evaluation of succinimide derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3W C Groutas, M J Brubaker, L S Chong, et al.
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