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Methods and Findings in Experimental and Clinical Pharmacology
|
January 1, 1985
Incorporation of 5-substituted pyrimidine nucleoside analogues into DNA of a thymidylate synthetase-deficient murine FM3A carcinoma cell line
J Balzarini, E De Clercq, D Ayusawa, et al.
Nucleosides, Nucleotides & Nucleic Acids
|
October 21, 2003
Novel nucleotide analogues as potential substrates for TMPK, a key enzyme in the metabolism of AZT
H C Müller, C Meier, J Balzarini, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 13, 2000
Thiosugars. Part 5: synthesis and biological activity of 1-(4-thio-L-arabinofuranosyl)-5-halopyrimidine nucleosides
J Wirsching, J Voss, J Balzarini, et al.
Molecular Pharmacology
|
February 13, 2001
Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase
B Degrève, R Esnouf, E De Clercq, et al.
Biochemical Pharmacology
|
October 17, 1998
Potent differentiation-inducing properties of the antiretroviral agent 9-(2-phosphonylmethoxyethyl) adenine (PMEA) in the rat choriocarcinoma (RCHO) tumor cell model
S Hatse, L Naesens, E De Clercq, et al.
AIDS Research and Human Retroviruses
|
March 10, 1998
A novel mutation (F227L) arises in the reverse transcriptase of human immunodeficiency virus type 1 on dose-escalating treatment of HIV type 1-infected cell cultures with the nonnucleoside reverse transcriptase inhibitor thiocarboxanilide UC-781
J Balzarini, H Pelemans, R Esnouf, et al.
Biochemical Pharmacology
|
June 15, 1980
Antiviral, antimetabolic and antineoplastic activities of 2'- or 3'-amino or -azido-substituted deoxyribonucleosides
E De Clercq, J Balzarini, J Descamps, et al.
Nucleosides & Nucleotides
|
August 5, 1999
An in situ pig liver esterase assay as a useful predictive tool for the likely in vitro anti viral activity of phosphoramidate pro-drugs
C Ballatore, C McGuigan, E De Clercq, et al.
Biochemical Pharmacology
|
July 28, 1999
N6-cyclopropyl-PMEDAP: a novel derivative of 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) with distinct metabolic, antiproliferative, and differentiation-inducing properties
S Hatse, L Naesens, E De Clercq, et al.
Journal of Medicinal Chemistry
|
May 7, 1999
cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system
C Meier, T Knispel, E De Clercq, et al.
Page
of 57
Search research articles
Search
Showing results (71-80 of 563) with videos related to
Sort By:
Page
of 57
Methods and Findings in Experimental and Clinical Pharmacology
|
January 1, 1985
Incorporation of 5-substituted pyrimidine nucleoside analogues into DNA of a thymidylate synthetase-deficient murine FM3A carcinoma cell line
J Balzarini, E De Clercq, D Ayusawa, et al.
Nucleosides, Nucleotides & Nucleic Acids
|
October 21, 2003
Novel nucleotide analogues as potential substrates for TMPK, a key enzyme in the metabolism of AZT
H C Müller, C Meier, J Balzarini, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 13, 2000
Thiosugars. Part 5: synthesis and biological activity of 1-(4-thio-L-arabinofuranosyl)-5-halopyrimidine nucleosides
J Wirsching, J Voss, J Balzarini, et al.
Molecular Pharmacology
|
February 13, 2001
Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase
B Degrève, R Esnouf, E De Clercq, et al.
Biochemical Pharmacology
|
October 17, 1998
Potent differentiation-inducing properties of the antiretroviral agent 9-(2-phosphonylmethoxyethyl) adenine (PMEA) in the rat choriocarcinoma (RCHO) tumor cell model
S Hatse, L Naesens, E De Clercq, et al.
AIDS Research and Human Retroviruses
|
March 10, 1998
A novel mutation (F227L) arises in the reverse transcriptase of human immunodeficiency virus type 1 on dose-escalating treatment of HIV type 1-infected cell cultures with the nonnucleoside reverse transcriptase inhibitor thiocarboxanilide UC-781
J Balzarini, H Pelemans, R Esnouf, et al.
Biochemical Pharmacology
|
June 15, 1980
Antiviral, antimetabolic and antineoplastic activities of 2'- or 3'-amino or -azido-substituted deoxyribonucleosides
E De Clercq, J Balzarini, J Descamps, et al.
Nucleosides & Nucleotides
|
August 5, 1999
An in situ pig liver esterase assay as a useful predictive tool for the likely in vitro anti viral activity of phosphoramidate pro-drugs
C Ballatore, C McGuigan, E De Clercq, et al.
Biochemical Pharmacology
|
July 28, 1999
N6-cyclopropyl-PMEDAP: a novel derivative of 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) with distinct metabolic, antiproliferative, and differentiation-inducing properties
S Hatse, L Naesens, E De Clercq, et al.
Journal of Medicinal Chemistry
|
May 7, 1999
cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system
C Meier, T Knispel, E De Clercq, et al.
Page
of 57