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Journal of Medicinal Chemistry
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September 9, 2010
Chemistry and pharmacological characterization of novel nitrogen analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-nicotinic acetylcholine receptor-selective partial agonists
Jianhua Liu, J Brek Eaton, Barbara Caldarone, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
April 19, 2005
Roles for nicotinic acetylcholine receptor subunit large cytoplasmic loop sequences in receptor expression and function
Yen-Ping Kuo, Lin Xu, J Brek Eaton, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
January 21, 2022
High-throughput cell-based assays for identifying antagonists of multiple smoking-associated human nicotinic acetylcholine receptor subtypes
Michelle Kassner, J Brek Eaton, Nanyun Tang, et al.
Journal of Medicinal Chemistry
|
June 6, 2014
Recent developments in novel antidepressants targeting α4β2-nicotinic acetylcholine receptors
Li-Fang Yu, Han-Kun Zhang, Barbara J Caldarone, et al.
ACS Medicinal Chemistry Letters
|
November 20, 2014
Enantiopure Cyclopropane-Bearing Pyridyldiazabicyclo[3.3.0]octanes as Selective α4β2-nAChR Ligands
Oluseye K Onajole, J Brek Eaton, Ronald J Lukas, et al.
ACS Chemical Neuroscience
|
April 2, 2016
Synthesis and Behavioral Studies of Chiral Cyclopropanes as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting an Antidepressant Profile. Part III
Oluseye K Onajole, Gian Paolo Vallerini, J Brek Eaton, et al.
The Journal of Biological Chemistry
|
December 9, 2015
Differential α4(+)/(-)β2 Agonist-binding Site Contributions to α4β2 Nicotinic Acetylcholine Receptor Function within and between Isoforms
Linda M Lucero, Maegan M Weltzin, J Brek Eaton, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
November 6, 2013
The unique α4+/-α4 agonist binding site in (α4)3(β2)2 subtype nicotinic acetylcholine receptors permits differential agonist desensitization pharmacology versus the (α4)2(β2)3 subtype
J Brek Eaton, Linda M Lucero, Harrison Stratton, et al.
Journal of Medicinal Chemistry
|
November 10, 2010
Nicotinic acetylcholine receptor efficacy and pharmacological properties of 3-(substituted phenyl)-2β-substituted tropanes
F Ivy Carroll, Bruce E Blough, S Wayne Mascarella, et al.
Journal of Medicinal Chemistry
|
October 25, 2012
Discovery of highly potent and selective α4β2-nicotinic acetylcholine receptor (nAChR) partial agonists containing an isoxazolylpyridine ether scaffold that demonstrate antidepressant-like activity. Part II
Li-Fang Yu, J Brek Eaton, Allison Fedolak, et al.
Page
of 3
Search research articles
Search
Showing results (1-10 of 25) with videos related to
Sort By:
Page
of 3
Journal of Medicinal Chemistry
|
September 9, 2010
Chemistry and pharmacological characterization of novel nitrogen analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-nicotinic acetylcholine receptor-selective partial agonists
Jianhua Liu, J Brek Eaton, Barbara Caldarone, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
April 19, 2005
Roles for nicotinic acetylcholine receptor subunit large cytoplasmic loop sequences in receptor expression and function
Yen-Ping Kuo, Lin Xu, J Brek Eaton, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
January 21, 2022
High-throughput cell-based assays for identifying antagonists of multiple smoking-associated human nicotinic acetylcholine receptor subtypes
Michelle Kassner, J Brek Eaton, Nanyun Tang, et al.
Journal of Medicinal Chemistry
|
June 6, 2014
Recent developments in novel antidepressants targeting α4β2-nicotinic acetylcholine receptors
Li-Fang Yu, Han-Kun Zhang, Barbara J Caldarone, et al.
ACS Medicinal Chemistry Letters
|
November 20, 2014
Enantiopure Cyclopropane-Bearing Pyridyldiazabicyclo[3.3.0]octanes as Selective α4β2-nAChR Ligands
Oluseye K Onajole, J Brek Eaton, Ronald J Lukas, et al.
ACS Chemical Neuroscience
|
April 2, 2016
Synthesis and Behavioral Studies of Chiral Cyclopropanes as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting an Antidepressant Profile. Part III
Oluseye K Onajole, Gian Paolo Vallerini, J Brek Eaton, et al.
The Journal of Biological Chemistry
|
December 9, 2015
Differential α4(+)/(-)β2 Agonist-binding Site Contributions to α4β2 Nicotinic Acetylcholine Receptor Function within and between Isoforms
Linda M Lucero, Maegan M Weltzin, J Brek Eaton, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
November 6, 2013
The unique α4+/-α4 agonist binding site in (α4)3(β2)2 subtype nicotinic acetylcholine receptors permits differential agonist desensitization pharmacology versus the (α4)2(β2)3 subtype
J Brek Eaton, Linda M Lucero, Harrison Stratton, et al.
Journal of Medicinal Chemistry
|
November 10, 2010
Nicotinic acetylcholine receptor efficacy and pharmacological properties of 3-(substituted phenyl)-2β-substituted tropanes
F Ivy Carroll, Bruce E Blough, S Wayne Mascarella, et al.
Journal of Medicinal Chemistry
|
October 25, 2012
Discovery of highly potent and selective α4β2-nicotinic acetylcholine receptor (nAChR) partial agonists containing an isoxazolylpyridine ether scaffold that demonstrate antidepressant-like activity. Part II
Li-Fang Yu, J Brek Eaton, Allison Fedolak, et al.
Page
of 3