Showing results (111-120 of 117) with videos related to
Sort By:
Pageof 12
You have reached the last page of results.This site can display upto 117 results.
The Journal of Biological Chemistry|June 25, 2008
The amyloid-beta rise and gamma-secretase inhibitor potency depend on the level of substrate expressionCatherine R Burton, Jere E Meredith, Donna M Barten, et al.Journal of Medicinal Chemistry|September 25, 2025
Discovery of Potent and Selective Reversible Ubiquitin-Like Modifier Activating Enzyme 5 Inhibitors Targeting the UFMylation PathwayJames J Mignone, Elizabeth A Jurica, Deepa Rajasekaran, et al.Journal of Medicinal Chemistry|March 9, 2022
Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic PainGuanglin Luo, Ling Chen, Walter A Kostich, et al.The Journal of Pharmacology and Experimental Therapeutics|September 29, 2017
Preclinical Characterization of (R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive DisorderLinda J Bristow, Jyoti Gulia, Michael R Weed, et al.Nature Communications|January 31, 2026
Covalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12CMatthew L Condakes, Zhuo Zhang, Derek B Danahy, et al.ACS Medicinal Chemistry Letters|May 26, 2018
BMS-986163, a Negative Allosteric Modulator of GluN2B with Potential Utility in Major Depressive DisorderLawrence R Marcin, Jayakumar Warrier, Srinivasan Thangathirupathy, et al.Journal of Medicinal Chemistry|March 8, 2022
Discovery of (S)-1-((2',6-Bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic PainGuanglin Luo, Ling Chen, Walter A Kostich, et al.Pageof 12