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Bioorganic & Medicinal Chemistry Letters|March 11, 2015
The discovery of potent agonists for GPR88, an orphan GPCR, for the potential treatment of CNS disordersYingzhi Bi, Carolyn D Dzierba, Cynthia Fink, et al.
Bioorganic & Medicinal Chemistry Letters|October 11, 2012
2-(N-Benzyl-N-phenylsulfonamido)alkyl amide derivatives as γ-secretase inhibitorsMichael F Parker, Donna M Barten, Carl P Bergstrom, et al.
Bioorganic & Medicinal Chemistry Letters|June 7, 2015
Biaryls as potent, tunable dual neurokinin 1 receptor antagonists and serotonin transporter inhibitorsAndrew P Degnan, George O Tora, Ying Han, et al.
Bioorganic & Medicinal Chemistry Letters|December 21, 2012
Design, optimization, and in vivo evaluation of a series of pyridine derivatives with dual NK1 antagonism and SERT inhibition for the treatment of depressionKevin W Gillman, Michael F Parker, Mark Silva, et al.
Bioorganic & Medicinal Chemistry Letters|October 14, 2003
Phosphonooxymethyl prodrugs of the broad spectrum antifungal azole, ravuconazole: synthesis and biological propertiesYasutsugu Ueda, John D Matiskella, Jerzy Golik, et al.
Bioorganic & Medicinal Chemistry Letters|September 18, 2007
Amino-caprolactam derivatives as gamma-secretase inhibitorsMichael F Parker, Joanne J Bronson, Donna M Barten, et al.
Bioorganic & Medicinal Chemistry Letters|July 26, 2011
Monosubstituted γ-lactam and conformationally constrained 1,3-diaminopropan-2-ol transition-state isostere inhibitors of β-secretase (BACE)Kenneth M Boy, Jason M Guernon, Jianliang Shi, et al.
ACS Chemical Neuroscience|April 15, 2016
Discovery, Synthesis, and Preclinical Characterization of N-(3-Chloro-4-fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-3-amine (VU0418506), a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4)Darren W Engers, Anna L Blobaum, Rocco D Gogliotti, et al.
Bioorganic & Medicinal Chemistry|December 5, 2016
Triazolopyridine ethers as potent, orally active mGlu2 positive allosteric modulators for treating schizophreniaMendi A Higgins, Lawrence R Marcin, F Christopher Zusi, et al.
Bioorganic & Medicinal Chemistry Letters|July 4, 2012
Synthesis and structure-activity relationships of pyrido[3,2-b]pyrazin-3(4H)-ones and pteridin-7(8H)-ones as corticotropin-releasing factor-1 receptor antagonistsCarolyn D Dzierba, Thais M Sielecki, Argyrios G Arvanitis, et al.
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