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Xenobiotica; the Fate of Foreign Compounds in Biological Systems|December 19, 2002
Comparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cellsJ Andrews, M F Abd-Ellah, N L Randolph, et al.European Journal of Clinical Pharmacology|March 12, 2017
Pharmacokinetics and pharmacogenetics of the MEK1/2 inhibitor, selumetinib, in Asian and Western healthy subjects: a pooled analysisAngela W Dymond, Cathy Elks, Paul Martin, et al.CPT: Pharmacometrics & Systems Pharmacology|March 23, 2017
Population Pharmacokinetics of Selumetinib and Its Metabolite N-desmethyl-selumetinib in Adult Patients With Advanced Solid Tumors and Children With Low-Grade GliomasY T Patel, V M Daryani, P Patel, et al.Blood|March 23, 2012
A phase 1 study of obinutuzumab induction followed by 2 years of maintenance in patients with relapsed CD20-positive B-cell malignanciesLaurie H Sehn, Sarit E Assouline, Douglas A Stewart, et al.Pharmaceutical Research|March 1, 2006
Determination of a human hepatic microsomal scaling factor for predicting in vivo drug clearanceNancy Hakooz, Kiyomi Ito, Helen Rawden, et al.Blood|October 17, 2015
Randomized phase 2 study of obinutuzumab monotherapy in symptomatic, previously untreated chronic lymphocytic leukemiaJohn C Byrd, Joseph M Flynn, Thomas J Kipps, et al.CPT: Pharmacometrics & Systems Pharmacology|October 10, 2015
Challenges and Opportunities for Quantitative Clinical Pharmacology in Cancer Immunotherapy: Something Old, Something New, Something Borrowed, and Something BlueM Stroh, D J Carlile, C-C Li, et al.Clinical Pharmacology and Therapeutics|June 27, 2025
Tocilizumab Dosing for Management of T Cell-Engaging Bispecific Antibody-Related CRS in Patients With R/R B-Cell NHLCandice Jamois, David C Turner, Leonid Gibiansky, et al.Journal of Clinical Periodontology|December 14, 2011
Mapping biological to clinical phenotypes during the development (21 days) and resolution (21 days) of experimental gingivitisAnn E Scott, Mike Milward, Gerard J Linden, et al.Current Drug Metabolism|February 3, 2007
Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liverZoe E Barter, Martin K Bayliss, Philip H Beaune, et al.Pageof 5