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Journal of Medicinal Chemistry
|
May 12, 2016
Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737)
James D Osborne, Thomas P Matthews, Tatiana McHardy, et al.
Journal of Medicinal Chemistry
|
April 11, 2020
Achieving <i>In Vivo</i> Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders
Benjamin R Bellenie, Kwai-Ming J Cheung, Ana Varela, et al.
Scientific Reports
|
November 4, 2022
Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays
Olivier A Pierrat, Manjuan Liu, Gavin W Collie, et al.
Journal of Medicinal Chemistry
|
June 2, 2022
Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 <i>In Vivo</i>
Rosemary Huckvale, Alice C Harnden, Kwai-Ming J Cheung, et al.
Journal of Medicinal Chemistry
|
November 21, 2007
4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer
Paul A Brough, Wynne Aherne, Xavier Barril, et al.
Conservation Physiology
|
July 21, 2025
Co-production and conservation physiology: outcomes, challenges and opportunities arising from reflections on diverse co-produced projects
Steven J Cooke, Nolan N Bett, Scott G Hinch, et al.
Immunity
|
May 24, 2024
A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
Jonathan Mannion, Valentina Gifford, Benjamin Bellenie, et al.
G3 (Bethesda, Md.)
|
November 7, 2019
Expression-Based Cell Lineage Analysis in <i>Drosophila</i> Through a Course-Based Research Experience for Early Undergraduates
John M Olson, Cory J Evans, Kathy T Ngo, et al.
Page
of 30
Search research articles
Search
Showing results (291-300 of 298) with videos related to
Sort By:
Page
of 30
You have reached the last page of results.
This site can display upto 298 results.
Journal of Medicinal Chemistry
|
May 12, 2016
Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737)
James D Osborne, Thomas P Matthews, Tatiana McHardy, et al.
Journal of Medicinal Chemistry
|
April 11, 2020
Achieving <i>In Vivo</i> Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders
Benjamin R Bellenie, Kwai-Ming J Cheung, Ana Varela, et al.
Scientific Reports
|
November 4, 2022
Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays
Olivier A Pierrat, Manjuan Liu, Gavin W Collie, et al.
Journal of Medicinal Chemistry
|
June 2, 2022
Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 <i>In Vivo</i>
Rosemary Huckvale, Alice C Harnden, Kwai-Ming J Cheung, et al.
Journal of Medicinal Chemistry
|
November 21, 2007
4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer
Paul A Brough, Wynne Aherne, Xavier Barril, et al.
Conservation Physiology
|
July 21, 2025
Co-production and conservation physiology: outcomes, challenges and opportunities arising from reflections on diverse co-produced projects
Steven J Cooke, Nolan N Bett, Scott G Hinch, et al.
Immunity
|
May 24, 2024
A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
Jonathan Mannion, Valentina Gifford, Benjamin Bellenie, et al.
G3 (Bethesda, Md.)
|
November 7, 2019
Expression-Based Cell Lineage Analysis in <i>Drosophila</i> Through a Course-Based Research Experience for Early Undergraduates
John M Olson, Cory J Evans, Kathy T Ngo, et al.
Page
of 30