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The Journal of Biological Chemistry|November 6, 2008
A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamicsFrancis S Willard, Zhen Zheng, Juan Guo, et al.Bioorganic & Medicinal Chemistry Letters|December 4, 2012
Further exploration of M₁ allosteric agonists: subtle structural changes abolish M₁ allosteric agonism and result in pan-mAChR orthosteric antagonismDouglas J Sheffler, Christian Sevel, Uyen Le, et al.Cell Metabolism|December 3, 2014
The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivoBrandon L Panaro, Iain R Tough, Maja S Engelstoft, et al.Bioorganic & Medicinal Chemistry Letters|September 21, 2011
Development of a highly selective, orally bioavailable and CNS penetrant M1 agonist derived from the MLPCN probe ML071Evan P Lebois, Gregory J Digby, Douglas J Sheffler, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|June 23, 2012
Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal modelsGregory J Digby, Meredith J Noetzel, Michael Bubser, et al.Brain : a Journal of Neurology|September 6, 2022
Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responsesEdward J Needham, Alexander L Ren, Richard J Digby, et al.Pageof 5