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Journal of Chemical Information and Modeling|May 13, 2009
Analysis of neighborhood behavior in lead optimization and array designGeorge Papadatos, Anthony W J Cooper, Visakan Kadirkamanathan, et al.Organic & Biomolecular Chemistry|May 27, 2016
Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosisNiall A Anderson, Ian B Campbell, Brendan J Fallon, et al.Neuron|March 10, 2001
CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampusY Huang, W Lu, D W Ali, et al.Journal of Medicinal Chemistry|January 28, 2017
Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C-C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase δ (PI3Kδ) InhibitorsCarolin Schwehm, Barrie Kellam, Aimie E Garces, et al.Chemmedchem|June 18, 2019
The Design of Potent, Selective and Drug-Like RGD αvβ1 Small-Molecule Inhibitors Derived from non-RGD α4β1 AntagonistsRichard J D Hatley, Tim N Barrett, Robert J Slack, et al.The Journal of Organic Chemistry|July 9, 2021
A Flexible, Practical, and Stereoselective Synthesis of Enantiomerically Pure trans-5-Oxohexahydropyrrolo[3,2-b]pyrroles (Pyrrolidine-trans-lactams), a New Class of Serine Protease Inhibitors, Using Acyliminium MethodologySimon J F Macdonald, Geoffrey D E Clarke, Michael D Dowle, et al.Journal of Medicinal Chemistry|February 7, 2017
Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous ModulatorsWillem-Jan Keune, Frances Potjewyd, Tatjana Heidebrecht, et al.Journal of Chemical Information and Modeling|September 30, 2010
Lead optimization using matched molecular pairs: inclusion of contextual information for enhanced prediction of HERG inhibition, solubility, and lipophilicityGeorge Papadatos, Muhammad Alkarouri, Valerie J Gillet, et al.ACS Medicinal Chemistry Letters|June 6, 2014
An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMSFélix Calderón, David Barros, José María Bueno, et al.Bioorganic & Medicinal Chemistry Letters|July 14, 2009
Highly tractable, sub-nanomolar non-steroidal glucocorticoid receptor agonistsKeith Biggadike, Matilde Caivano, Margaret Clackers, et al.Pageof 19