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J F MacDonald

Showing results (181-190 of 210) with videos related to

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The Journal of Organic Chemistry|July 9, 2021
A Flexible, Practical, and Stereoselective Synthesis of Enantiomerically Pure <i>trans</i>-5-Oxohexahydropyrrolo[3,2-<i>b</i>]pyrroles (Pyrrolidine-<i>trans</i>-lactams), a New Class of Serine Protease Inhibitors, Using Acyliminium MethodologySimon J F Macdonald, Geoffrey D E Clarke, Michael D Dowle, et al.
Journal of Medicinal Chemistry|February 7, 2017
Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous ModulatorsWillem-Jan Keune, Frances Potjewyd, Tatjana Heidebrecht, et al.
Journal of Chemical Information and Modeling|September 30, 2010
Lead optimization using matched molecular pairs: inclusion of contextual information for enhanced prediction of HERG inhibition, solubility, and lipophilicityGeorge Papadatos, Muhammad Alkarouri, Valerie J Gillet, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMSFélix Calderón, David Barros, José María Bueno, et al.
Bioorganic & Medicinal Chemistry Letters|July 14, 2009
Highly tractable, sub-nanomolar non-steroidal glucocorticoid receptor agonistsKeith Biggadike, Matilde Caivano, Margaret Clackers, et al.
Bioorganic & Medicinal Chemistry Letters|March 10, 2004
Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidaseKeith G Watson, Rachel Cameron, Rob J Fenton, et al.
Journal of Medicinal Chemistry|October 17, 2024
Core Modifications of GSK3335103 toward Orally Bioavailable α<sub>v</sub>β<sub>6</sub> Inhibitors with Improved Synthetic TractabilityHeather F Hryczanek, John Barrett, Tim N Barrett, et al.
Journal of Medicinal Chemistry|December 17, 2016
Structure-Activity Relationships of Small Molecule Autotaxin Inhibitors with a Discrete Binding ModeLisa M Miller, Willem-Jan Keune, Diana Castagna, et al.
Journal of Medicinal Chemistry|September 10, 2019
Discovery of an Orally Bioavailable Pan αv Integrin Inhibitor for Idiopathic Pulmonary FibrosisNiall A Anderson, Sebastien Campos, Sharon Butler, et al.
Journal of Medicinal Chemistry|July 8, 2005
Design and synthesis of new nonsteroidal glucocorticoid modulators through application of an "agreement docking" methodMike Barker, Margaret Clackers, Derek A Demaine, et al.
Pageof 21

Showing results (181-190 of 210) with videos related to

Sort By:
Pageof 21
The Journal of Organic Chemistry|July 9, 2021
A Flexible, Practical, and Stereoselective Synthesis of Enantiomerically Pure <i>trans</i>-5-Oxohexahydropyrrolo[3,2-<i>b</i>]pyrroles (Pyrrolidine-<i>trans</i>-lactams), a New Class of Serine Protease Inhibitors, Using Acyliminium MethodologySimon J F Macdonald, Geoffrey D E Clarke, Michael D Dowle, et al.
Journal of Medicinal Chemistry|February 7, 2017
Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous ModulatorsWillem-Jan Keune, Frances Potjewyd, Tatjana Heidebrecht, et al.
Journal of Chemical Information and Modeling|September 30, 2010
Lead optimization using matched molecular pairs: inclusion of contextual information for enhanced prediction of HERG inhibition, solubility, and lipophilicityGeorge Papadatos, Muhammad Alkarouri, Valerie J Gillet, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMSFélix Calderón, David Barros, José María Bueno, et al.
Bioorganic & Medicinal Chemistry Letters|July 14, 2009
Highly tractable, sub-nanomolar non-steroidal glucocorticoid receptor agonistsKeith Biggadike, Matilde Caivano, Margaret Clackers, et al.
Bioorganic & Medicinal Chemistry Letters|March 10, 2004
Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidaseKeith G Watson, Rachel Cameron, Rob J Fenton, et al.
Journal of Medicinal Chemistry|October 17, 2024
Core Modifications of GSK3335103 toward Orally Bioavailable α<sub>v</sub>β<sub>6</sub> Inhibitors with Improved Synthetic TractabilityHeather F Hryczanek, John Barrett, Tim N Barrett, et al.
Journal of Medicinal Chemistry|December 17, 2016
Structure-Activity Relationships of Small Molecule Autotaxin Inhibitors with a Discrete Binding ModeLisa M Miller, Willem-Jan Keune, Diana Castagna, et al.
Journal of Medicinal Chemistry|September 10, 2019
Discovery of an Orally Bioavailable Pan αv Integrin Inhibitor for Idiopathic Pulmonary FibrosisNiall A Anderson, Sebastien Campos, Sharon Butler, et al.
Journal of Medicinal Chemistry|July 8, 2005
Design and synthesis of new nonsteroidal glucocorticoid modulators through application of an "agreement docking" methodMike Barker, Margaret Clackers, Derek A Demaine, et al.
Pageof 21