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J F MacDonald

Showing results (191-200 of 210) with videos related to

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ACS Medicinal Chemistry Letters|June 6, 2014
Cyclopropyl Carboxamides: A New Oral Antimalarial Series Derived from the Tres Cantos Anti-Malarial Set (TCAMS)Lourdes Rueda, Isabel Castellote, Julia Castro-Pichel, et al.
Bioorganic & Medicinal Chemistry Letters|July 10, 2007
Non-steroidal glucocorticoid agonists: the discovery of aryl pyrazoles as A-ring mimeticsMargaret Clackers, Diane M Coe, Derek A Demaine, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 14, 2009
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptorKeith Biggadike, Randy K Bledsoe, Diane M Coe, et al.
Journal of Medicinal Chemistry|September 13, 2024
Discovery and Development of Highly Potent and Orally Bioavailable Nonpeptidic α<sub>v</sub>β<sub>6</sub> Integrin InhibitorsPanayiotis A Procopiou, John Barrett, Matthew H J Crawford, et al.
Bioorganic & Medicinal Chemistry Letters|January 25, 2011
Discovery of a potent series of non-steroidal non α-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicityHawa Diallo, Davina C Angell, Heather A Barnett, et al.
Journal of Medicinal Chemistry|August 6, 2019
Profile of a Highly Selective Quaternized Pyrrolidine Betaine α<sub>v</sub>β<sub>6</sub> Integrin Inhibitor-(3<i>S</i>)-3-(3-(3,5-Dimethyl-1<i>H</i>-pyrazol-1-yl)phenyl)-4-((1<i>S</i> and 1<i>R</i>,3<i>R</i>)-1-methyl-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate Synthesized by Stereoselective MethylationTim N Barrett, Jonathan A Taylor, Daniel Barker, et al.
Bioorganic & Medicinal Chemistry Letters|November 21, 2008
Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonistsHeather A Barnett, Diane M Coe, Tony W J Cooper, et al.
Drug Discovery Today|September 21, 2013
A practical drug discovery project at the undergraduate levelM Jonathan Fray, Simon J F Macdonald, Ian R Baldwin, et al.
Journal of Medicinal Chemistry|November 28, 2007
Nonsteroidal glucocorticoid agonists: tetrahydronaphthalenes with alternative steroidal A-ring mimetics possessing dissociated (transrepression/transactivation) efficacy selectivityKeith Biggadike, Mohamed Boudjelal, Margaret Clackers, et al.
Journal of Medicinal Chemistry|August 23, 2002
Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151)Simon J F Macdonald, Michael D Dowle, Lee A Harrison, et al.
Pageof 21

Showing results (191-200 of 210) with videos related to

Sort By:
Pageof 21
ACS Medicinal Chemistry Letters|June 6, 2014
Cyclopropyl Carboxamides: A New Oral Antimalarial Series Derived from the Tres Cantos Anti-Malarial Set (TCAMS)Lourdes Rueda, Isabel Castellote, Julia Castro-Pichel, et al.
Bioorganic & Medicinal Chemistry Letters|July 10, 2007
Non-steroidal glucocorticoid agonists: the discovery of aryl pyrazoles as A-ring mimeticsMargaret Clackers, Diane M Coe, Derek A Demaine, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 14, 2009
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptorKeith Biggadike, Randy K Bledsoe, Diane M Coe, et al.
Journal of Medicinal Chemistry|September 13, 2024
Discovery and Development of Highly Potent and Orally Bioavailable Nonpeptidic α<sub>v</sub>β<sub>6</sub> Integrin InhibitorsPanayiotis A Procopiou, John Barrett, Matthew H J Crawford, et al.
Bioorganic & Medicinal Chemistry Letters|January 25, 2011
Discovery of a potent series of non-steroidal non α-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicityHawa Diallo, Davina C Angell, Heather A Barnett, et al.
Journal of Medicinal Chemistry|August 6, 2019
Profile of a Highly Selective Quaternized Pyrrolidine Betaine α<sub>v</sub>β<sub>6</sub> Integrin Inhibitor-(3<i>S</i>)-3-(3-(3,5-Dimethyl-1<i>H</i>-pyrazol-1-yl)phenyl)-4-((1<i>S</i> and 1<i>R</i>,3<i>R</i>)-1-methyl-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate Synthesized by Stereoselective MethylationTim N Barrett, Jonathan A Taylor, Daniel Barker, et al.
Bioorganic & Medicinal Chemistry Letters|November 21, 2008
Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonistsHeather A Barnett, Diane M Coe, Tony W J Cooper, et al.
Drug Discovery Today|September 21, 2013
A practical drug discovery project at the undergraduate levelM Jonathan Fray, Simon J F Macdonald, Ian R Baldwin, et al.
Journal of Medicinal Chemistry|November 28, 2007
Nonsteroidal glucocorticoid agonists: tetrahydronaphthalenes with alternative steroidal A-ring mimetics possessing dissociated (transrepression/transactivation) efficacy selectivityKeith Biggadike, Mohamed Boudjelal, Margaret Clackers, et al.
Journal of Medicinal Chemistry|August 23, 2002
Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151)Simon J F Macdonald, Michael D Dowle, Lee A Harrison, et al.
Pageof 21