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Journal of Medicinal Chemistry
|
March 14, 2012
Discovery of ((S)-5-(methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone as a potent and selective I(Kur) inhibitor
Heather J Finlay, John Lloyd, Wayne Vaccaro, et al.
Journal of Molecular Biology
|
February 23, 2013
Comprehensive interrogation of a minimalist synthetic CDR-H3 library and its ability to generate antibodies with therapeutic potential
Ciara M Mahon, Matthew A Lambert, Jacob Glanville, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 2, 2015
Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies
Sue Townsend, Brian J Fennell, James R Apgar, et al.
Gastroenterology
|
October 13, 2006
Increased serum levels of complement C3a anaphylatoxin indicate the presence of colorectal tumors
Jens K Habermann, Uwe J Roblick, Brian T Luke, et al.
Journal of Molecular Biology
|
March 17, 2009
Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions
William J Finlay, Orla Cunningham, Matthew A Lambert, et al.
Frontiers in Oncology
|
January 24, 2014
Evidence That GRIN2A Mutations in Melanoma Correlate with Decreased Survival
Stacey Ann N D'mello, Jack U Flanagan, Taryn N Green, et al.
Journal of Medicinal Chemistry
|
March 10, 2021
Discovery of a Hydroxypyridinone APJ Receptor Agonist as a Clinical Candidate
James A Johnson, Soong-Hoon Kim, Ji Jiang, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 24, 2018
Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors
Carol H Hu, Tammy C Wang, Jennifer X Qiao, et al.
Mabs
|
December 23, 2017
Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics
Lindsay B Avery, Jason Wade, Mengmeng Wang, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 16, 2014
Diphenylpyridylethanamine (DPPE)-based aminoheterocycles as cholesteryl ester transfer protein inhibitors
Yufeng Wang, Wu Yang, Heather J Finlay, et al.
Page
of 40
Search research articles
Search
Showing results (371-380 of 394) with videos related to
Sort By:
Page
of 40
Journal of Medicinal Chemistry
|
March 14, 2012
Discovery of ((S)-5-(methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone as a potent and selective I(Kur) inhibitor
Heather J Finlay, John Lloyd, Wayne Vaccaro, et al.
Journal of Molecular Biology
|
February 23, 2013
Comprehensive interrogation of a minimalist synthetic CDR-H3 library and its ability to generate antibodies with therapeutic potential
Ciara M Mahon, Matthew A Lambert, Jacob Glanville, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 2, 2015
Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies
Sue Townsend, Brian J Fennell, James R Apgar, et al.
Gastroenterology
|
October 13, 2006
Increased serum levels of complement C3a anaphylatoxin indicate the presence of colorectal tumors
Jens K Habermann, Uwe J Roblick, Brian T Luke, et al.
Journal of Molecular Biology
|
March 17, 2009
Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions
William J Finlay, Orla Cunningham, Matthew A Lambert, et al.
Frontiers in Oncology
|
January 24, 2014
Evidence That GRIN2A Mutations in Melanoma Correlate with Decreased Survival
Stacey Ann N D'mello, Jack U Flanagan, Taryn N Green, et al.
Journal of Medicinal Chemistry
|
March 10, 2021
Discovery of a Hydroxypyridinone APJ Receptor Agonist as a Clinical Candidate
James A Johnson, Soong-Hoon Kim, Ji Jiang, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 24, 2018
Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors
Carol H Hu, Tammy C Wang, Jennifer X Qiao, et al.
Mabs
|
December 23, 2017
Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics
Lindsay B Avery, Jason Wade, Mengmeng Wang, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 16, 2014
Diphenylpyridylethanamine (DPPE)-based aminoheterocycles as cholesteryl ester transfer protein inhibitors
Yufeng Wang, Wu Yang, Heather J Finlay, et al.
Page
of 40