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Journal of Medicinal Chemistry|February 11, 2025
Identification of Structurally Novel KRASG12C Inhibitors through Covalent DNA-Encoded Library ScreeningDavid Huang, Francesco Manoni, Zhen Sun, et al.Journal of Medicinal Chemistry|July 14, 2026
Expanding Addressable KRAS Mutations through the Structure- and Property-Based Design of Dual-State (GDP/GTP), Reversible Pan-KRAS InhibitorsRyan P Wurz, Jennifer R Allen, John G Allen, et al.Journal of Medicinal Chemistry|March 27, 2025
Discovery of AMG 193, an MTA-Cooperative PRMT5 Inhibitor for the Treatment of MTAP-Deleted CancersLiping H Pettus, Matthew Bourbeau, Nuria A Tamayo, et al.Journal of Medicinal Chemistry|December 11, 2019
Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid TumorsBrian A Lanman, Jennifer R Allen, John G Allen, et al.Pageof 3