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Showing results (21-30 of 31) with videos related to

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The Journal of Biological Chemistry|November 20, 2008
Human Dicer binds short single-strand and double-strand RNA with high affinity and interacts with different regions of the nucleic acidsWalt F Lima, Heather Murray, Josh G Nichols, et al.
Nucleic Acid Therapeutics|April 1, 2016
Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout MiceColby S Shemesh, Rosie Z Yu, Hans J Gaus, et al.
Journal of Medicinal Chemistry|January 30, 2010
Antisense oligonucleotides containing conformationally constrained 2',4'-(N-methoxy)aminomethylene and 2',4'-aminooxymethylene and 2'-O,4'-C-aminomethylene bridged nucleoside analogues show improved potency in animal modelsThazha P Prakash, Andrew Siwkowski, Charles R Allerson, et al.
Nucleic Acids Research|February 4, 2017
Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptorKarsten Schmidt, Thazha P Prakash, Aaron J Donner, et al.
ACS Omega|November 17, 2025
Synthesis, Incorporation, and Translation Properties of Threose Nucleic Acid Modified Trinucleotide Cap AnalogsAlexander Pontarelli, Guillermo Vasquez, Wuxia Fu, et al.
Bioorganic & Medicinal Chemistry Letters|August 25, 2004
Formation of 4,4'-dimethoxytrityl-C-phosphonate oligonucleotidesDaniel C Capaldi, Hans J Gaus, Recaldo L Carty, et al.
Nucleic Acids Research|May 26, 2019
Fatty acid conjugation enhances potency of antisense oligonucleotides in muscleThazha P Prakash, Adam E Mullick, Richard G Lee, et al.
Bioconjugate Chemistry|May 27, 2015
Efficient Synthesis and Biological Evaluation of 5'-GalNAc Conjugated Antisense OligonucleotidesMichael E Østergaard, Jinghua Yu, Garth A Kinberger, et al.
Molecular Therapy. Nucleic Acids|May 11, 2016
Elucidation of the Biotransformation Pathways of a Galnac3-conjugated Antisense Oligonucleotide in Rats and MonkeysColby S Shemesh, Rosie Z Yu, Hans J Gaus, et al.
Nucleic Acids Research|May 12, 2019
Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primatesMichael E Østergaard, Michaela Jackson, Audrey Low, et al.
Pageof 4

Showing results (21-30 of 31) with videos related to

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Pageof 4
The Journal of Biological Chemistry|November 20, 2008
Human Dicer binds short single-strand and double-strand RNA with high affinity and interacts with different regions of the nucleic acidsWalt F Lima, Heather Murray, Josh G Nichols, et al.
Nucleic Acid Therapeutics|April 1, 2016
Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout MiceColby S Shemesh, Rosie Z Yu, Hans J Gaus, et al.
Journal of Medicinal Chemistry|January 30, 2010
Antisense oligonucleotides containing conformationally constrained 2',4'-(N-methoxy)aminomethylene and 2',4'-aminooxymethylene and 2'-O,4'-C-aminomethylene bridged nucleoside analogues show improved potency in animal modelsThazha P Prakash, Andrew Siwkowski, Charles R Allerson, et al.
Nucleic Acids Research|February 4, 2017
Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptorKarsten Schmidt, Thazha P Prakash, Aaron J Donner, et al.
ACS Omega|November 17, 2025
Synthesis, Incorporation, and Translation Properties of Threose Nucleic Acid Modified Trinucleotide Cap AnalogsAlexander Pontarelli, Guillermo Vasquez, Wuxia Fu, et al.
Bioorganic & Medicinal Chemistry Letters|August 25, 2004
Formation of 4,4'-dimethoxytrityl-C-phosphonate oligonucleotidesDaniel C Capaldi, Hans J Gaus, Recaldo L Carty, et al.
Nucleic Acids Research|May 26, 2019
Fatty acid conjugation enhances potency of antisense oligonucleotides in muscleThazha P Prakash, Adam E Mullick, Richard G Lee, et al.
Bioconjugate Chemistry|May 27, 2015
Efficient Synthesis and Biological Evaluation of 5'-GalNAc Conjugated Antisense OligonucleotidesMichael E Østergaard, Jinghua Yu, Garth A Kinberger, et al.
Molecular Therapy. Nucleic Acids|May 11, 2016
Elucidation of the Biotransformation Pathways of a Galnac3-conjugated Antisense Oligonucleotide in Rats and MonkeysColby S Shemesh, Rosie Z Yu, Hans J Gaus, et al.
Nucleic Acids Research|May 12, 2019
Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primatesMichael E Østergaard, Michaela Jackson, Audrey Low, et al.
Pageof 4