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Bioorganic & Medicinal Chemistry Letters|October 5, 2010
Discovery of a vorapaxar analog with increased aqueous solubilityYan Xia, Samuel Chackalamannil, William J Greenlee, et al.Bioorganic & Medicinal Chemistry Letters|May 4, 2011
Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetesYan Xia, Samuel Chackalamannil, William J Greenlee, et al.Journal of Medicinal Chemistry|March 6, 1992
Synthesis and use of 3-amino-4-phenyl-2-piperidones and 4-amino-2-benzazepin-3-ones as conformationally restricted phenylalanine isosteres in renin inhibitorsS E de Laszlo, B L Bush, J J Doyle, et al.Bioorganic & Medicinal Chemistry Letters|July 11, 2006
Himbacine derived thrombin receptor (PAR-1) antagonists: structure-activity relationship of the lactone ringYan Xia, Samuel Chackalamannil, Tze-Ming Chan, et al.Journal of Hypertension|March 1, 1990
Acute hypotensive responses to peptide inhibitors of renin in conscious monkeys: an effect on blood pressure independent of plasma renin inhibitionL W Schaffer, T W Schorn, R J Winquist, et al.European Journal of Pharmacology|December 29, 1995
In vitro pharmacology of an angiotensin AT1 receptor antagonist with balanced affinity for AT2 receptorsR S Chang, V J Lotti, T B Chen, et al.Bioorganic & Medicinal Chemistry Letters|October 6, 2009
Novel orally active morpholine N-arylsulfonamides gamma-secretase inhibitors with low CYP 3A4 liabilityHubert Josien, Thomas Bara, Murali Rajagopalan, et al.Journal of Medicinal Chemistry|May 2, 2008
Discovery of a novel, orally active himbacine-based thrombin receptor antagonist (SCH 530348) with potent antiplatelet activitySamuel Chackalamannil, Yuguang Wang, William J Greenlee, et al.Circulation|April 11, 2001
Effects of L-749,329, an ET(A)/ET(B) endothelin receptor antagonist, in a porcine coronary artery injury model of vascular restenosisW R Huckle, M D Drag, W R Acker, et al.Journal of Medicinal Chemistry|August 20, 1993
Triazolinones as nonpeptide angiotensin II antagonists. 1. Synthesis and evaluation of potent 2,4,5-trisubstituted triazolinonesL L Chang, W T Ashton, K L Flanagan, et al.Pageof 30